| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Teenage Mutant Ninja Turtles II: The Secret of the Ooze | $26,728,908 | - | 2,868 | - | $9,319 | $26,728,908 | 1 | New Line Cinema | true | false |
| 2 | 1 | The Silence of the Lambs | $9,767,863 | -5.5% | 1,608 | +8 | $6,074 | $81,338,357 | 7 | Orion Pictures | false | false |
| 3 | 8 | Dances with Wolves | $6,545,293 | +59.4% | 1,538 | -7 | $4,255 | $139,106,936 | 20 | Orion Pictures | false | false |
| 4 | 2 | New Jack City | $6,339,163 | -18.5% | 905 | +18 | $7,004 | $24,147,354 | 3 | Warner Bros. | false | false |
| 5 | 4 | Class Action | $5,702,141 | +2.9% | 1,108 | +330 | $5,146 | $11,246,060 | 2 | Twentieth Century Fox | false | false |
| 6 | 3 | Sleeping with the Enemy | $5,692,044 | -9.4% | 1,517 | -28 | $3,752 | $75,622,630 | 7 | Twentieth Century Fox | false | false |
| 7 | 5 | The Hard Way | $4,132,360 | -20.9% | 1,629 | +2 | $2,536 | $17,546,130 | 3 | Universal Pictures | false | false |
| 8 | 9 | Home Alone | $4,059,636 | +17.4% | 1,757 | +344 | $2,310 | $254,344,614 | 19 | Twentieth Century Fox | false | false |
| 9 | 7 | The Doors | $3,348,078 | -25.8% | 1,186 | -50 | $2,823 | $27,933,346 | 4 | TriStar Pictures | false | false |
| 10 | 6 | The Perfect Weapon | $3,194,888 | -37.4% | 1,229 | - | $2,599 | $8,296,220 | 2 | Paramount Pictures | false | false |
| 11 | 10 | Guilty by Suspicion | $2,502,420 | -20.3% | 817 | - | $3,062 | $5,643,400 | 2 | Warner Bros. | false | false |
| 12 | 11 | If Looks Could Kill | $2,061,453 | -27.5% | 838 | - | $2,459 | $4,905,643 | 2 | Warner Bros. | false | false |
| 13 | - | The Long Walk Home | $1,410,426 | - | 270 | - | $5,223 | $1,679,389 | 14 | Miramax | false | false |
| 14 | 14 | Kindergarten Cop | $975,050 | -3.1% | 548 | +3 | $1,779 | $84,261,023 | 14 | Universal Pictures | false | false |
| 15 | - | Ghost | $342,736 | - | 205 | -53 | $1,671 | $216,588,143 | 37 | Paramount Pictures | false | false |
| 16 | - | Defending Your Life | $137,751 | - | 3 | - | $45,917 | $137,751 | 1 | Warner Bros. | true | false |
| 17 | - | Mister Johnson | $15,705 | - | 1 | - | $15,705 | $15,705 | 1 | Avenue Pictures Productions | true | false |
| 18 | - | Scissors | $2,368 | - | 1 | - | $2,368 | $2,368 | 1 | - | true | false |
