| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | The Twilight Saga: Eclipse | $300,531,751 | 4,468 | $64,832,191 | 4,468 | Jun 30, 2010 | Summit Entertainment |
| 2 | The Twilight Saga: New Moon | $296,623,634 | 4,124 | $142,839,137 | 4,024 | Nov 20, 2009 | Summit Entertainment |
| 3 | The Twilight Saga: Breaking Dawn - Part 1 | $281,287,133 | 4,066 | $138,122,261 | 4,061 | Nov 18, 2011 | Summit Entertainment |
| 4 | A Quiet Place | $188,024,361 | 3,808 | $50,203,562 | 3,508 | Apr 6, 2018 | Paramount Pictures |
| 5 | Mr. & Mrs. Smith | $186,336,279 | 3,451 | $50,342,878 | 3,424 | Jun 10, 2005 | Twentieth Century Fox |
| 6 | There's Something About Mary | $176,484,651 | 2,555 | $13,740,644 | 2,186 | Jul 15, 1998 | Twentieth Century Fox |
| 7 | Scooby-Doo | $153,294,164 | 3,447 | $54,155,312 | 3,447 | Jun 14, 2002 | Warner Bros. |
| 8 | Good Will Hunting | $138,433,435 | 2,203 | $272,912 | 7 | Dec 5, 1997 | Miramax |
| 9 | Traffic | $124,115,725 | 1,755 | $184,725 | 4 | Dec 27, 2000 | USA Films |
| 10 | Dick Tracy | $103,738,726 | 2,332 | $22,543,911 | 2,332 | Jun 15, 1990 | Walt Disney Studios Motion Pictures |
| 11 | Vanilla Sky | $100,618,344 | 2,842 | $25,015,518 | 2,742 | Dec 14, 2001 | Paramount Pictures |
| 12 | Me, Myself & Irene | $90,570,999 | 3,087 | $24,209,385 | 3,019 | Jun 23, 2000 | Twentieth Century Fox |
| 13 | Days of Thunder | $82,670,733 | 2,307 | $15,490,445 | 2,307 | Jun 29, 1990 | Paramount Pictures |
| 14 | Far and Away | $58,883,840 | 1,885 | $10,194,520 | 1,583 | May 22, 1992 | Universal Pictures |
| 15 | Edward Scissorhands | $56,362,352 | 1,372 | $159,622 | 2 | Dec 7, 1990 | Twentieth Century Fox |
| 16 | Just Married | $56,127,162 | 2,769 | $17,548,993 | 2,766 | Jan 10, 2003 | Twentieth Century Fox |
| 17 | Eyes Wide Shut | $55,691,208 | 2,483 | $21,706,163 | 2,411 | Jul 16, 1999 | Warner Bros. |
| 18 | Bugsy | $49,114,016 | 1,253 | $140,358 | 4 | Dec 13, 1991 | TriStar Pictures |
| 19 | Cobra | $49,042,224 | 2,131 | $12,653,032 | 2,131 | May 23, 1986 | Warner Bros. |
| 20 | Cruel Intentions | $38,328,567 | 2,312 | $13,020,565 | 2,312 | Mar 5, 1999 | Sony Pictures Releasing |
| 21 | Bounce | $36,805,288 | 2,028 | $11,423,716 | 1,918 | Nov 17, 2000 | Miramax |
| 22 | Proof of Life | $32,598,931 | 2,705 | $10,207,869 | 2,705 | Dec 8, 2000 | Warner Bros. |
| 23 | Overboard | $26,713,187 | 1,135 | $1,880,006 | 1,126 | Dec 18, 1987 | Metro-Goldwyn-Mayer (MGM) |
| 24 | Innerspace | $25,893,810 | 1,603 | $4,739,913 | 1,603 | Jul 3, 1987 | Warner Bros. |
| 25 | Crocodile Dundee in Los Angeles | $25,635,682 | 2,166 | $7,714,362 | 2,123 | Apr 20, 2001 | Paramount Pictures |
| 26 | Dream House | $21,302,340 | 2,664 | $8,129,355 | 2,661 | Sep 30, 2011 | Universal Pictures |
| 27 | Volunteers | $19,875,740 | 1,560 | $5,184,360 | 1,560 | Aug 16, 1985 | TriStar Pictures |
| 28 | Mortal Thoughts | $18,784,957 | 1,196 | $6,068,524 | 963 | Apr 19, 1991 | Columbia Pictures |
| 29 | Love Affair | $18,272,894 | 1,585 | $5,438,758 | 1,585 | Oct 21, 1994 | Warner Bros. |
| 30 | Going the Distance | $17,804,299 | 3,030 | $6,884,964 | 3,030 | Sep 3, 2010 | Warner Bros. |
| 31 | Bringing Out the Dead | $16,797,191 | 1,967 | $6,193,052 | 1,936 | Oct 22, 1999 | Paramount Pictures |
| 32 | The Getaway | $16,094,974 | 1,659 | $5,806,515 | 1,659 | Feb 11, 1994 | Universal Pictures |
| 33 | Hit and Run | $13,749,300 | 2,870 | $4,526,222 | 2,870 | Aug 22, 2012 | Open Road Films (II) |
| 34 | D.O.A. | $12,706,478 | 908 | $3,751,432 | 875 | Mar 18, 1988 | Walt Disney Studios Motion Pictures |
| 35 | The Light Between Oceans | $12,545,979 | 1,500 | $4,765,838 | 1,500 | Sep 2, 2016 | Walt Disney Studios Motion Pictures |
| 36 | Gattaca | $12,532,777 | 1,279 | $4,320,202 | 1,279 | Oct 24, 1997 | Sony Pictures Releasing |
| 37 | The Marrying Man | $12,454,768 | 1,343 | $4,030,749 | 1,340 | Apr 5, 1991 | Walt Disney Studios Motion Pictures |
| 38 | Wild Orchid | $11,060,485 | 822 | $2,622,637 | 819 | Apr 27, 1990 | Triumph Releasing Corporation |
| 39 | Flesh and Bone | $9,709,451 | 1,200 | $4,517,066 | 1,200 | Nov 5, 1993 | Paramount Pictures |
| 40 | She's So Lovely | $7,281,450 | 844 | $3,020,015 | 824 | Aug 27, 1997 | Miramax |
| 41 | Trapped | $7,073,251 | 2,227 | $3,210,765 | 2,227 | Sep 20, 2002 | Sony Pictures Releasing |
| 42 | Swing Shift | $6,650,206 | 814 | $2,270,136 | 710 | Apr 13, 1984 | Warner Bros. |
| 43 | Gigli | $6,087,542 | 2,215 | $3,753,518 | 2,215 | Aug 1, 2003 | Revolution Studios |
| 44 | Princess Caraboo | $3,062,530 | 301 | $1,005,287 | 301 | Sep 16, 1994 | TriStar Pictures |
| 45 | Sidewalks of New York | $2,402,652 | 224 | $545,132 | 99 | Nov 23, 2001 | Paramount Classics |
| 46 | Shanghai Surprise | $2,315,683 | 401 | $729,885 | 401 | Aug 29, 1986 | Metro-Goldwyn-Mayer (MGM) |
| 47 | Two Much | $1,141,556 | 348 | $592,871 | 348 | Mar 15, 1996 | Walt Disney Studios Motion Pictures |
| 48 | Knight Moves | $923,418 | 420 | $459,900 | 420 | Jan 22, 1993 | Republic Pictures (I) |
| 49 | Bodies, Rest & Motion | $764,724 | 6 | $75,957 | 6 | Apr 9, 1993 | New Line Cinema |
| 50 | By the Sea | $538,460 | 142 | $96,250 | 10 | Nov 13, 2015 | Universal Pictures |
| 51 | Kill Me Again | $283,694 | 221 | $66,013 | 221 | Oct 27, 1989 | - |
| 52 | The Experts | $169,203 | 100 | $169,203 | 100 | Jan 13, 1989 | Paramount Pictures |
