| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | The Twilight Saga: Eclipse | $300,531,751 | 4,468 | $64,832,191 | 4,468 | Jun 30, 2010 | Summit Entertainment |
| 2 | The Twilight Saga: New Moon | $296,623,634 | 4,124 | $142,839,137 | 4,024 | Nov 20, 2009 | Summit Entertainment |
| 3 | The Twilight Saga: Breaking Dawn - Part 2 | $292,324,737 | 4,070 | $141,067,634 | 4,070 | Nov 16, 2012 | Lionsgate Films |
| 4 | The Twilight Saga: Breaking Dawn - Part 1 | $281,287,133 | 4,066 | $138,122,261 | 4,061 | Nov 18, 2011 | Summit Entertainment |
| 5 | Twilight | $192,769,854 | 3,649 | $69,637,740 | 3,419 | Nov 21, 2008 | Summit Entertainment |
| 6 | Hotel Transylvania 2 | $169,700,110 | 3,768 | $48,464,322 | 3,754 | Sep 25, 2015 | Sony Pictures Releasing |
| 7 | Hotel Transylvania 3: Summer Vacation | $167,510,016 | 4,267 | $44,076,225 | 4,267 | Jul 13, 2018 | Sony Pictures Releasing |
| 8 | Hotel Transylvania | $148,313,048 | 3,375 | $42,522,194 | 3,349 | Sep 28, 2012 | Sony Pictures Releasing |
| 9 | Van Helsing | $120,177,084 | 3,580 | $51,748,040 | 3,575 | May 7, 2004 | Universal Pictures |
| 10 | Interview with the Vampire: The Vampire Chronicles | $105,264,608 | 2,604 | $36,389,705 | 2,604 | Nov 11, 1994 | Warner Bros. |
| 11 | Bram Stoker's Dracula | $82,522,790 | 2,491 | $30,521,679 | 2,491 | Nov 13, 1992 | Columbia Pictures |
| 12 | Blade II | $82,348,319 | 2,707 | $32,528,016 | 2,707 | Mar 22, 2002 | New Line Cinema |
| 13 | Dark Shadows | $79,727,149 | 3,755 | $29,685,274 | 3,755 | May 11, 2012 | Warner Bros. |
| 14 | Blade | $70,087,718 | 2,389 | $17,073,856 | 2,322 | Aug 21, 1998 | New Line Cinema |
| 15 | Underworld: Awakening | $62,321,039 | 3,078 | $25,306,725 | 3,078 | Jan 20, 2012 | Screen Gems |
| 16 | Underworld: Evolution | $62,318,875 | 3,207 | $26,857,181 | 3,207 | Jan 20, 2006 | Screen Gems |
| 17 | Dracula Untold | $56,280,355 | 2,900 | $23,514,615 | 2,885 | Oct 10, 2014 | Universal Pictures |
| 18 | Blade: Trinity | $52,411,906 | 2,912 | $16,100,000 | 2,912 | Dec 8, 2004 | New Line Cinema |
| 19 | Underworld | $51,970,690 | 2,928 | $21,753,759 | 2,915 | Sep 19, 2003 | Screen Gems |
| 20 | Underworld: Rise of the Lycans | $45,802,315 | 2,942 | $20,828,511 | 2,942 | Jan 23, 2009 | Screen Gems |
| 21 | 30 Days of Night | $39,569,000 | 2,859 | $15,951,902 | 2,855 | Oct 19, 2007 | Sony Pictures Releasing |
| 22 | Abraham Lincoln: Vampire Hunter | $37,519,139 | 3,109 | $16,306,974 | 3,108 | Jun 22, 2012 | Twentieth Century Fox |
| 23 | Vampires Suck | $36,661,504 | 3,233 | $12,202,831 | 3,233 | Aug 18, 2010 | Twentieth Century Fox |
| 24 | Dracula 2000 | $33,022,767 | 2,204 | $8,636,567 | 2,204 | Dec 22, 2000 | Miramax |
| 25 | The Lost Boys | $32,222,567 | 1,249 | $5,236,318 | 1,027 | Jul 31, 1987 | Warner Bros. |
| 26 | Underworld: Blood Wars | $30,353,973 | 3,070 | $13,688,751 | 3,070 | Jan 6, 2017 | Screen Gems |
| 27 | Queen of the Damned | $30,336,800 | 2,511 | $14,757,535 | 2,511 | Feb 22, 2002 | Warner Bros. |
| 28 | Daybreakers | $30,101,577 | 2,523 | $15,146,692 | 2,523 | Jan 8, 2010 | Lionsgate Films |
| 29 | Priest | $29,137,000 | 2,864 | $14,953,664 | 2,864 | May 13, 2011 | Screen Gems |
| 30 | From Dusk Till Dawn | $25,836,616 | 2,007 | $10,240,805 | 2,004 | Jan 19, 1996 | Miramax |
| 31 | Fright Night | $24,922,237 | 1,545 | $6,118,543 | 1,542 | Aug 2, 1985 | Columbia Pictures |
| 32 | Vampires | $20,308,772 | 1,793 | $9,106,497 | 1,793 | Oct 30, 1998 | Sony Pictures Releasing |
| 33 | Dracula | $20,158,970 | 395 | $3,141,281 | 395 | Jul 20, 1979 | Universal Pictures |
| 34 | Vampire in Brooklyn | $19,751,736 | 2,307 | $7,045,379 | 2,307 | Oct 27, 1995 | Paramount Pictures |
| 35 | Fright Night | $18,302,607 | 3,114 | $7,714,388 | 3,114 | Aug 19, 2011 | Walt Disney Studios Motion Pictures |
| 36 | Buffy the Vampire Slayer | $16,624,456 | 1,981 | $4,515,541 | 1,959 | Jul 31, 1992 | Twentieth Century Fox |
| 37 | Cirque du Freak: The Vampire's Assistant | $13,869,515 | 2,754 | $6,293,205 | 2,754 | Oct 23, 2009 | Universal Pictures |
| 38 | The Little Vampire | $13,572,400 | 2,009 | $5,719,627 | 2,009 | Oct 27, 2000 | New Line Cinema |
| 39 | Let Me In | $12,134,935 | 2,042 | $5,147,479 | 2,020 | Oct 1, 2010 | Overture Films |
| 40 | Dracula: Dead and Loving It | $10,772,144 | 1,425 | $2,708,298 | 1,425 | Dec 22, 1995 | Sony Pictures Releasing |
| 41 | Once Bitten | $10,000,000 | 1,095 | $4,025,657 | 1,095 | Nov 15, 1985 | The Samuel Goldwyn Company |
| 42 | Shadow of the Vampire | $8,293,784 | 513 | $150,171 | 6 | Dec 29, 2000 | Lionsgate Films |
| 43 | Vampire Academy | $7,791,979 | 2,676 | $3,921,742 | 2,676 | Feb 7, 2014 | The Weinstein Company |
| 44 | The Forsaken | $7,288,451 | 1,514 | $3,020,159 | 1,514 | Apr 27, 2001 | Screen Gems |
| 45 | Transylvania 6-5000 | $7,196,872 | 701 | $2,507,542 | 701 | Nov 8, 1985 | New World Pictures |
| 46 | The Hunger | $5,979,292 | 775 | $1,832,898 | 775 | Apr 29, 1983 | Metro-Goldwyn-Mayer (MGM) |
| 47 | Bordello of Blood | $5,781,045 | 1,695 | $2,634,170 | 1,694 | Aug 16, 1996 | Universal Pictures |
| 48 | Innocent Blood | $4,943,279 | 1,326 | $1,857,658 | 1,326 | Sep 25, 1992 | Warner Bros. |
| 49 | Vamp | $4,941,117 | 1,104 | $2,187,458 | 1,104 | Jul 18, 1986 | New World Pictures |
| 50 | Near Dark | $3,369,307 | 429 | $635,789 | 262 | Oct 2, 1987 | De Laurentiis Entertainment Group (DEG) |
| 51 | Fright Night Part 2 | $2,983,784 | 161 | $548,231 | 148 | May 19, 1989 | New Century |
| 52 | BloodRayne | $2,405,420 | 985 | $1,550,000 | 985 | Jan 6, 2006 | Romar Entertainment |
| 53 | Def by Temptation | $2,218,579 | 57 | $54,582 | 11 | May 11, 1990 | Troma |
| 54 | Let the Right One In | $2,122,065 | 53 | $49,295 | 4 | Oct 24, 2008 | Magnolia Pictures |
| 55 | Only Lovers Left Alive | $1,879,534 | 95 | $87,989 | 4 | Apr 11, 2014 | Sony Pictures Classics |
| 56 | The Lair of the White Worm | $1,189,315 | 32 | $22,155 | 2 | Oct 21, 1988 | Vestron Pictures |
| 57 | Dylan Dog: Dead of Night | $1,186,538 | 875 | $754,779 | 875 | Apr 29, 2011 | - |
| 58 | Vampire's Kiss | $725,131 | 45 | $96,699 | 29 | Jun 2, 1989 | Hemdale |
| 59 | Cronos | $621,392 | 28 | $17,538 | 2 | Apr 1, 1994 | October Films |
| 60 | A Girl Walks Home Alone at Night | $491,910 | 19 | - | - | Nov 21, 2014 | Kino Lorber |
| 61 | Nadja | $443,169 | 14 | $23,846 | 1 | Aug 25, 1995 | October Films |
| 62 | Thirst | $318,574 | 17 | $55,889 | 4 | Jul 31, 2009 | Focus Features |
| 63 | The Addiction | $307,308 | 14 | $46,448 | 7 | Oct 6, 1995 | October Films |
| 64 | Blood: The Last Vampire | $257,412 | 20 | $110,029 | 20 | Jul 10, 2009 | The Samuel Goldwyn Company |
| 65 | My Best Friend Is a Vampire | $174,380 | 170 | $174,380 | 170 | May 6, 1988 | - |
| 66 | Vampire Hunter D: Bloodlust | $151,086 | 12 | $25,521 | 6 | Sep 21, 2001 | - |
| 67 | The Night Flier | $125,397 | 95 | $91,549 | 95 | Feb 6, 1998 | New Line Cinema |
| 68 | Byzantium | $89,237 | 13 | $16,643 | 6 | Jun 28, 2013 | IFC Films |
| 69 | Freaks of Nature | $70,958 | 107 | $42,713 | 107 | Oct 30, 2015 | Sony Pictures Releasing |
| 70 | Dracula: Pages from a Virgin's Diary | $55,365 | 2 | $4,784 | 1 | May 14, 2003 | Zeitgeist Films |
| 71 | Stake Land | $33,245 | 5 | $7,258 | 1 | Apr 22, 2011 | IFC Films |
| 72 | Therapy for a Vampire | $30,115 | 9 | $3,361 | 2 | Jun 10, 2016 | Music Box Films |
| 73 | Eternal | $28,089 | 9 | $4,129 | 1 | Aug 26, 2005 | Regent Releasing |
| 74 | Immortality | $25,648 | 1 | $10,281 | 1 | Jul 14, 2000 | Miramax |
| 75 | Bonnie & Clyde vs. Dracula | $25,027 | 3 | $5,688 | 3 | Mar 11, 2011 | Indican Pictures |
| 76 | The Reflecting Skin | $17,042 | 2 | $5,958 | 2 | Jun 28, 1991 | Miramax |
| 77 | Kiss of the Damned | $14,752 | 7 | $2,723 | 2 | May 3, 2013 | Magnolia Pictures |
| 78 | Dracula 3D | $8,139 | 6 | $3,085 | 6 | Oct 4, 2013 | IFC Films |
| 79 | The Moth Diaries | $3,838 | 2 | $2,276 | 2 | Apr 20, 2012 | IFC Films |
| 80 | Vamps | $3,361 | 1 | $548 | 1 | Nov 2, 2012 | Anchor Bay Films |
| 81 | I Kissed a Vampire | $1,794 | 11 | $1,380 | 11 | Mar 30, 2012 | Monterey Media |
