| Rank
| Title
| Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor
|
|---|
| 1 | The Twilight Saga: Eclipse | $300,531,751 | 4,468 | $64,832,191 | 4,468 | Jun 30, 2010 | Summit Entertainment |
| 2 | The Twilight Saga: New Moon | $296,623,634 | 4,124 | $142,839,137 | 4,024 | Nov 20, 2009 | Summit Entertainment |
| 3 | The Twilight Saga: Breaking Dawn - Part 2 | $292,324,737 | 4,070 | $141,067,634 | 4,070 | Nov 16, 2012 | Lionsgate Films |
| 4 | The Twilight Saga: Breaking Dawn - Part 1 | $281,287,133 | 4,066 | $138,122,261 | 4,061 | Nov 18, 2011 | Summit Entertainment |
| 5 | Wolf | $65,002,597 | 2,117 | $17,911,366 | 2,117 | Jun 17, 1994 | Columbia Pictures |
| 6 | Underworld: Awakening | $62,321,039 | 3,078 | $25,306,725 | 3,078 | Jan 20, 2012 | Screen Gems |
| 7 | Underworld: Evolution | $62,318,875 | 3,207 | $26,857,181 | 3,207 | Jan 20, 2006 | Screen Gems |
| 8 | The Wolfman | $61,979,680 | 3,223 | $31,479,235 | 3,222 | Feb 12, 2010 | Universal Pictures |
| 9 | Underworld | $51,970,690 | 2,928 | $21,753,759 | 2,915 | Sep 19, 2003 | Screen Gems |
| 10 | Underworld: Rise of the Lycans | $45,802,315 | 2,942 | $20,828,511 | 2,942 | Jan 23, 2009 | Screen Gems |
| 11 | Red Riding Hood | $37,662,162 | 3,030 | $14,005,335 | 3,030 | Mar 11, 2011 | Warner Bros. |
| 12 | Teen Wolf | $33,086,611 | 1,425 | $6,120,348 | 1,416 | Aug 23, 1985 | Atlantic Releasing Corporation |
| 13 | An American Werewolf in London | $30,565,292 | 870 | $3,786,512 | 870 | Aug 21, 1981 | Universal Pictures |
| 14 | Underworld: Blood Wars | $30,353,973 | 3,070 | $13,688,751 | 3,070 | Jan 6, 2017 | Screen Gems |
| 15 | An American Werewolf in Paris | $26,570,463 | 1,731 | $7,600,878 | 1,728 | Dec 25, 1997 | Walt Disney Studios Motion Pictures |
| 16 | Cursed | $19,297,522 | 2,805 | $9,600,000 | 2,805 | Feb 25, 2005 | Dimension Films |
| 17 | The Howling | $17,985,893 | - | - | - | Apr 10, 1981 | Embassy Pictures |
| 18 | Silver Bullet | $12,361,866 | 1,285 | $4,013,563 | 1,285 | Oct 11, 1985 | Paramount Pictures |
| 19 | Wolfen | $10,626,725 | 967 | $3,037,911 | 967 | Jul 24, 1981 | Warner Bros. |
| 20 | Teen Wolf Too | $7,888,703 | 1,540 | $2,709,160 | 1,540 | Nov 20, 1987 | Atlantic Releasing Corporation |
| 21 | The Company of Wolves | $4,389,334 | 995 | $2,234,776 | 995 | Apr 19, 1985 | Cannon Film Distributors |
| 22 | Blood and Chocolate | $3,526,847 | 1,200 | $2,074,300 | 1,200 | Jan 26, 2007 | Metro-Goldwyn-Mayer (MGM) |
| 23 | Bad Moon | $1,055,525 | 825 | $607,081 | 825 | Nov 1, 1996 | Warner Bros. |
| 24 | Skinwalkers | $1,018,965 | 745 | $565,000 | 745 | Aug 10, 2007 | After Dark Films |
| 25 | A Werewolf Boy | $342,922 | 20 | - | - | Nov 30, 2012 | CJ Entertainment |
| 26 | Ginger Snaps 2: Unleashed | $80,372 | 53 | $80,372 | 53 | Jan 30, 2004 | - |
| 27 | Wolves | $12,139 | 12 | - | - | Nov 14, 2014 | Ketchup Entertainment |
| 28 | Lycan | $9,110 | 5 | $4,970 | 5 | Aug 18, 2017 | Parade Deck Films |
| 29 | Ginger Snaps | $2,554 | 1 | $1,430 | 1 | Oct 26, 2001 | Cinema Village Features |
