| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | National Treasure: Book of Secrets | - | - | - | $13,656,128 | 3,832 | $219,964,115 | Dec 21 | Walt Disney Studios Motion Pictures | false |
| 2 | I Am Legend | - | - | - | $9,781,154 | 3,648 | $256,393,010 | Dec 14 | Warner Bros. | false |
| 3 | Aliens vs. Predator: Requiem | - | - | - | $9,515,615 | 2,617 | $41,797,066 | Dec 25 | Twentieth Century Fox | false |
| 4 | Alvin and the Chipmunks | - | - | - | $6,038,795 | 3,499 | $217,326,974 | Dec 14 | Twentieth Century Fox | false |
| 5 | Charlie Wilson's War | - | - | - | $4,338,875 | 2,594 | $66,661,095 | Dec 21 | Universal Pictures | false |
| 6 | The Great Debaters | - | - | - | $3,639,116 | 1,290 | $30,236,407 | Dec 25 | Metro-Goldwyn-Mayer (MGM) | false |
| 7 | Sweeney Todd: The Demon Barber of Fleet Street | - | - | - | $3,166,183 | 1,507 | $52,898,073 | Dec 21 | DreamWorks | false |
| 8 | Juno | - | - | - | $2,823,083 | 2,534 | $143,495,265 | Dec 5 | Fox Searchlight Pictures | false |
| 9 | The Water Horse | - | - | - | $2,385,644 | 2,777 | $40,946,255 | Dec 25 | Revolution Studios | false |
| 10 | P.S. I Love You | - | - | - | $2,085,237 | 2,471 | $53,695,808 | Dec 21 | Warner Bros. | false |
| 11 | Walk Hard: The Dewey Cox Story | - | - | - | $1,527,972 | 2,650 | $18,317,151 | Dec 21 | Sony Pictures Releasing | false |
| 12 | The Golden Compass | - | - | - | $1,280,000 | 3,528 | $70,107,728 | Dec 7 | New Line Cinema | true |
| 13 | Enchanted | - | - | - | $1,137,657 | 3,730 | $127,807,262 | Nov 21 | Walt Disney Studios Motion Pictures | false |
| 14 | Atonement | - | - | - | $632,947 | 1,400 | $50,927,067 | Dec 7 | Focus Features | false |
| 15 | The Kite Runner | - | - | - | $522,719 | 715 | $15,800,078 | Dec 14 | Paramount Vantage | false |
| 16 | No Country for Old Men | - | - | - | $521,777 | 2,037 | $74,283,625 | Nov 9 | Miramax | false |
| 17 | This Christmas | - | - | - | $213,757 | 1,921 | $49,121,934 | Nov 21 | Screen Gems | false |
| 18 | The Perfect Holiday | - | - | - | $167,773 | 1,307 | $5,812,781 | Dec 12 | Yari Film Group Releasing | false |
| 19 | The Bucket List | - | - | - | $161,966 | 2,915 | $93,466,502 | Dec 25 | Warner Bros. | false |
| 20 | The Savages | - | - | - | $124,544 | 201 | $6,623,082 | Nov 28 | Fox Searchlight Pictures | false |
| 21 | Beowulf | - | - | - | $95,362 | 3,249 | $82,280,579 | Nov 16 | Paramount Pictures | false |
| 22 | Fred Claus | - | - | - | $92,005 | 3,603 | $72,006,777 | Nov 9 | Warner Bros. | false |
| 23 | August Rush | - | - | - | $82,212 | 2,310 | $31,664,162 | Nov 21 | Warner Bros. | false |
| 24 | Bee Movie | - | - | - | $80,964 | 3,984 | $126,631,277 | Nov 2 | DreamWorks | false |
| 25 | American Gangster | - | - | - | $59,400 | 3,110 | $130,164,645 | Nov 2 | Universal Pictures | false |
| 26 | Persepolis | - | - | - | $37,118 | 536 | $4,445,756 | Dec 25 | Sony Pictures Classics | false |
| 27 | I'm Not There | - | - | - | $33,246 | 149 | $4,017,609 | Nov 21 | The Weinstein Company | false |
| 28 | Hitman | - | - | - | $28,768 | 2,468 | $39,687,694 | Nov 21 | Twentieth Century Fox | false |
| 29 | Into the Wild | - | - | - | $22,627 | 660 | $18,354,356 | Sep 21 | Paramount Vantage | false |
| 30 | Margot at the Wedding | - | - | - | $18,945 | 121 | $1,959,420 | Nov 16 | Paramount Vantage | false |
| 31 | The Polar Express 2007 IMAX Release | - | - | - | $18,726 | 32 | $2,483,757 | Oct 5 | Warner Bros. | false |
| 32 | Mr. Magorium's Wonder Emporium | - | - | - | $18,723 | 3,168 | $32,061,555 | Nov 16 | Twentieth Century Fox | false |
| 33 | Awake | - | - | - | $16,402 | 2,023 | $14,377,198 | Nov 30 | Metro-Goldwyn-Mayer (MGM) | false |
| 34 | Michael Clayton | - | - | - | $13,353 | 2,585 | $49,033,882 | Oct 5 | Warner Bros. | false |
| 35 | Lust, Caution | - | - | - | $8,506 | 143 | $4,604,982 | Sep 28 | Focus Features | false |
| 36 | Lars and the Real Girl | - | - | - | $7,406 | 321 | $5,972,884 | Oct 12 | Metro-Goldwyn-Mayer (MGM) | false |
| 37 | Deep Sea | - | - | - | $7,308 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 38 | The Darjeeling Limited | - | - | - | $5,046 | 698 | $11,902,715 | Sep 29 | Fox Searchlight Pictures | false |
| 39 | Blade Runner The Final Cut (2007 re-release) | - | - | - | $4,638 | 20 | $1,548,502 | Oct 5 | Warner Bros. | false |
| 40 | The Mist | - | - | - | $3,906 | 2,423 | $25,594,957 | Nov 21 | Metro-Goldwyn-Mayer (MGM) | false |
| 41 | Bella | - | - | - | $2,526 | 457 | $8,070,537 | Oct 26 | Roadside Attractions | false |
| 42 | Control | - | - | - | $1,624 | 29 | $872,252 | Oct 10 | The Weinstein Company | false |
| 43 | Lions for Lambs | - | - | - | $809 | 2,216 | $15,002,854 | Nov 9 | United Artists | false |
| 44 | The Assassination of Jesse James by the Coward Robert Ford | - | - | - | $678 | 301 | $3,909,149 | Sep 21 | Warner Bros. | false |
| 45 | Death at a Funeral | - | - | - | $92 | 324 | $8,580,428 | Aug 17 | Metro-Goldwyn-Mayer (MGM) | false |
