| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Cars | - | - | - | $23,493,495 | 513 | $30,858,370 | Jul 28 | Buena Vista International | false |
| 2 | Pirates of the Caribbean: Dead Man's Chest | - | - | - | $23,041,076 | 520 | $98,668,102 | Jul 7 | Buena Vista International | false |
| 3 | Miami Vice | - | - | - | $13,621,002 | 412 | $13,994,361 | Aug 4 | United International Pictures | false |
| 4 | Monster House | - | - | - | $9,874,472 | 430 | $12,462,338 | Aug 11 | Sony Pictures Releasing | false |
| 5 | The Break-Up | - | - | - | $9,190,352 | 380 | $19,289,594 | Jul 21 | United International Pictures | false |
| 6 | Superman Returns | - | - | - | $7,873,144 | 481 | $30,157,106 | Jul 14 | Warner Bros. | false |
| 7 | Garfield: A Tail of Two Kitties | - | - | - | $7,033,102 | 344 | $12,212,030 | Jul 21 | 20th Century Fox International | false |
| 8 | Nacho Libre | - | - | - | $6,922,727 | 366 | $7,332,945 | Aug 11 | United International Pictures | false |
| 9 | Stormbreaker | - | - | - | $6,406,595 | 378 | $12,872,046 | Jul 21 | Entertainment Film Distributors | false |
| 10 | Snakes on a Plane | - | - | - | $6,325,244 | 359 | $7,994,471 | Aug 18 | Entertainment Film Distributors | false |
| 11 | You, Me and Dupree | - | - | - | $6,255,245 | 412 | $15,250,701 | Aug 25 | United International Pictures | false |
| 12 | John Tucker Must Die | - | - | - | $5,500,111 | 272 | $7,273,502 | Aug 18 | 20th Century Fox International | false |
| 13 | My Super Ex-Girlfriend | - | - | - | $5,494,428 | 291 | $5,499,940 | Aug 4 | 20th Century Fox International | false |
| 14 | Over the Hedge | - | - | - | $4,086,263 | 504 | $25,901,994 | Jun 30 | United International Pictures | false |
| 15 | Kabhi Alvida Naa Kehna | - | - | - | $3,610,712 | 62 | $3,904,073 | Aug 11 | Yash Raj Films | false |
| 16 | The Ant Bully | - | - | - | $3,415,817 | 370 | $3,971,526 | Aug 4 | Warner Bros. | false |
| 17 | Lady in the Water | - | - | - | $2,098,341 | 287 | $2,105,760 | Aug 11 | Warner Bros. | false |
| 18 | Severance | - | - | - | $1,932,058 | 302 | $3,221,022 | Aug 25 | Pathé | false |
| 19 | Volver | - | - | - | $1,648,141 | 87 | $5,676,144 | Aug 25 | Pathé | false |
| 20 | The Wind that Shakes the Barley | - | - | - | $1,591,516 | 106 | $4,778,816 | Jun 23 | Pathé | false |
| 21 | The Da Vinci Code | - | - | - | $1,416,123 | 523 | $55,532,575 | May 19 | Sony Pictures Releasing | false |
| 22 | Harsh Times | - | - | - | $1,385,068 | 217 | $1,425,718 | Aug 18 | Pathé | false |
| 23 | A Scanner Darkly | - | - | - | $1,318,815 | 104 | $1,778,192 | Aug 18 | Warner Bros. | false |
| 24 | Deep Sea | - | - | - | $976,228 | 3 | $2,869,929 | Mar 3 | IMAX | false |
| 25 | Stay Alive | - | - | - | $502,463 | 160 | $763,551 | Jul 28 | United International Pictures | false |
| 26 | Omkara | - | - | - | $351,466 | 30 | $521,568 | Jul 28 | Eros Worldwide | false |
| 27 | Aap Ki Khatir | - | - | - | $307,642 | 36 | $417,460 | Aug 25 | Venus | false |
| 28 | The Notorious Bettie Page | - | - | - | $268,712 | 16 | $293,593 | Aug 4 | Icon Film Distribution Australia | false |
| 29 | Angel-A | - | - | - | $254,445 | 27 | $380,937 | Jul 28 | Optimum Releasing | false |
| 30 | Little Fish | - | - | - | $204,860 | 20 | $442,735 | Jul 21 | Tartan | false |
| 31 | Thank You for Smoking | - | - | - | $204,014 | 107 | $2,176,400 | Jun 16 | 20th Century Fox International | false |
| 32 | United 93 | - | - | - | $198,329 | 278 | $5,374,823 | Jun 2 | United International Pictures | false |
| 33 | Just My Luck | - | - | - | $137,991 | 326 | $3,827,440 | Jun 30 | 20th Century Fox International | false |
| 34 | Three Times | - | - | - | $124,278 | 5 | $165,647 | Aug 4 | Artificial Eye | false |
| 35 | The Protector | - | - | - | $110,676 | 41 | $176,832 | Jul 28 | Contender Entertainment Group | false |
| 36 | Shaadi Karke Phas Gaya Yaar | - | - | - | $109,216 | 13 | $109,216 | Aug 4 | Eros Worldwide | false |
| 37 | The Lake House | - | - | - | $86,373 | 343 | $5,278,471 | Jun 23 | Warner Bros. | false |
| 38 | Renaissance | - | - | - | $85,018 | 10 | $132,165 | Jul 28 | Pathé | false |
| 39 | Heading South | - | - | - | $81,241 | 15 | $317,059 | Jul 7 | Soda Pictures | false |
| 40 | The Front | - | - | - | $72,720 | 30 | $85,699 | Aug 25 | Buena Vista International | false |
| 41 | Friends with Money | - | - | - | $72,104 | 51 | $889,902 | May 26 | Sony Pictures Releasing | false |
| 42 | Tideland | - | - | - | $67,126 | 7 | $109,578 | Aug 11 | Revolver Entertainment | false |
| 43 | Curious George | - | - | - | $67,118 | 319 | $2,763,105 | May 26 | United International Pictures | false |
| 44 | The Cave of the Yellow Dog | - | - | - | $61,263 | 17 | $258,893 | Jun 30 | Tartan | false |
| 45 | Atomised | - | - | - | $59,892 | 24 | $189,719 | Jul 14 | Momentum Pictures | false |
| 46 | Krrish | - | - | - | $51,186 | 46 | $1,301,123 | Jun 23 | Adlabs Films | false |
| 47 | Look Both Ways | - | - | - | $50,133 | 10 | $59,413 | Aug 25 | Tartan | false |
| 48 | X-Men: The Last Stand | - | - | - | $47,277 | 470 | $35,645,846 | May 26 | 20th Century Fox International | false |
| 49 | Golmaal Fun Unlimited | - | - | - | $44,697 | 28 | $348,928 | Jul 14 | Venus | false |
| 50 | Wilderness | - | - | - | $44,684 | 8 | $44,684 | Aug 11 | Momentum Pictures | false |
| 51 | The Third Man 2006 Re-release | - | - | - | $41,365 | 1 | $41,365 | Aug 11 | Optimum Releasing | false |
| 52 | Innocent Voices | - | - | - | $38,614 | 5 | $38,614 | Aug 11 | The Works UK Distribution | false |
| 53 | Alpha Male | - | - | - | $33,699 | 4 | $33,699 | Aug 11 | Verve Pictures | false |
| 54 | Anthony Kaun Hai? | - | - | - | $33,002 | 10 | $33,002 | Aug 4 | Adlabs Films | false |
| 55 | Paper Clips 2006 Re-release | - | - | - | $31,013 | 3 | $31,013 | Aug 4 | Lionsgate | false |
| 56 | Brick | - | - | - | $30,716 | 49 | $1,330,381 | May 12 | Optimum Releasing | false |
| 57 | The Death of Mr. Lazarescu | - | - | - | $27,746 | 4 | $86,494 | Jul 14 | Tartan | false |
| 58 | Wah-Wah | - | - | - | $25,218 | 45 | $366,925 | Jun 2 | Lionsgate | false |
| 59 | The Fallen Idol | - | - | - | $20,100 | 1 | $32,064 | Jul 28 | Pathé | false |
| 60 | Quai des illusions | - | - | - | $19,907 | 16 | $297,112 | Jun 2 | Tartan | false |
| 61 | District B13 | - | - | - | $18,987 | 74 | $509,975 | Jul 7 | Momentum Pictures | false |
| 62 | Forty Shades of Blue | - | - | - | $18,652 | 7 | $83,666 | Jun 30 | Artificial Eye | false |
| 63 | Ballets Russes | - | - | - | $17,520 | 20 | $261,752 | Apr 21 | Revolver Entertainment | false |
| 64 | Akeelah and the Bee | - | - | - | $15,712 | 106 | $15,712 | Aug 18 | Lionsgate | false |
| 65 | Something Something... Unnakum Ennakum | - | - | - | $15,257 | 2 | $23,828 | Jul 28 | Ayngaran International | false |
| 66 | Stray Dogs 2006 Re-release | - | - | - | $13,639 | 2 | $13,639 | Aug 18 | Artificial Eye | false |
| 67 | Enron: The Smartest Guys in the Room | - | - | - | $11,031 | 25 | $303,736 | Apr 28 | Lionsgate | false |
| 68 | Oklahoma! 2006 Re-release | - | - | - | $9,840 | 4 | $15,520 | Aug 25 | Park Circus | false |
| 69 | Regular Lovers | - | - | - | $3,788 | 1 | $9,929 | Jul 21 | Artificial Eye | false |
| 70 | Who Killed the Electric Car? | - | - | - | $2,928 | 3 | $2,928 | Aug 4 | Sony Pictures Releasing | false |
| 71 | Rebecca 2006 Re-release | - | - | - | $2,799 | 2 | $50,700 | Jun 30 | British Film Institute (BFI) | false |
| 72 | C.S.A.: The Confederate States of America | - | - | - | $1,776 | 1 | $20,884 | Aug 4 | Tartan | false |
