| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Toy Story 3 | - | - | - | $42,555,768 | 569 | $116,625,632 | Jul 23 | Walt Disney Pictures | false |
| 2 | Inception | - | - | - | $18,753,784 | 472 | $56,566,947 | Jul 16 | Warner Bros. | false |
| 3 | Knight and Day 2010 Re-release | - | - | - | $14,099,616 | 441 | $14,099,616 | Aug 6 | 20th Century Fox International | false |
| 4 | Step Up 3D | - | - | - | $11,537,610 | 401 | $11,537,610 | Aug 6 | Universal Pictures International (UPI) | false |
| 5 | The Expendables | - | - | - | $10,588,769 | 453 | $15,969,695 | Aug 20 | Lionsgate | false |
| 6 | The Karate Kid | - | - | - | $10,382,592 | 446 | $19,762,070 | Jul 30 | Sony Pictures Releasing | false |
| 7 | The A-Team | - | - | - | $9,679,814 | 453 | $15,281,498 | Jul 30 | 20th Century Fox International | false |
| 8 | Salt | - | - | - | $6,809,609 | 413 | $11,321,253 | Aug 20 | Sony Pictures Releasing | false |
| 9 | The Last Airbender | - | - | - | $6,564,441 | 450 | $6,564,441 | Aug 13 | Paramount Pictures International | false |
| 10 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $6,171,863 | 480 | $7,570,467 | Aug 6 | Warner Bros. | false |
| 11 | Piranha 3D | - | - | - | $5,107,469 | 354 | $6,903,929 | Aug 20 | Entertainment Film Distributors | false |
| 12 | The Sorcerer's Apprentice | - | - | - | $4,692,994 | 406 | $5,423,182 | Aug 13 | Walt Disney Pictures | false |
| 13 | Marmaduke | - | - | - | $4,564,671 | 457 | $9,019,305 | Aug 20 | 20th Century Fox International | false |
| 14 | Grown Ups | - | - | - | $3,117,633 | 401 | $12,161,427 | Aug 27 | Sony Pictures Releasing | false |
| 15 | Shrek Forever After | - | - | - | $2,699,147 | 539 | $51,056,068 | Jul 2 | Paramount Pictures International | false |
| 16 | Scott Pilgrim vs. the World | - | - | - | $2,492,536 | 414 | $8,445,713 | Aug 27 | Universal Pictures International (UPI) | false |
| 17 | The Twilight Saga: Eclipse | - | - | - | $2,112,191 | 526 | $45,709,785 | Jul 9 | Entertainment One | false |
| 18 | Tinker Bell and the Great Fairy Rescue | - | - | - | $1,164,811 | 236 | $2,396,006 | Aug 13 | Walt Disney Pictures | false |
| 19 | Diary of a Wimpy Kid | - | - | - | $1,042,596 | 372 | $4,283,601 | Aug 27 | 20th Century Fox International | false |
| 20 | Avatar | - | - | - | $969,500 | 503 | $147,646,580 | Dec 18 | 20th Century Fox International | false |
| 21 | The Girl Who Played with Fire | - | - | - | $628,974 | 141 | $2,556,558 | Aug 27 | Momentum Pictures | false |
| 22 | Gainsbourg: A Heroic Life | - | - | - | $513,826 | 59 | $725,732 | Jul 30 | Optimum Releasing | false |
| 23 | The Rebound | - | - | - | $353,625 | 306 | $1,792,015 | Jan 8 | Momentum Pictures | false |
| 24 | The Illusionist | - | - | - | $256,297 | 42 | $1,417,299 | Aug 20 | Warner Bros. | false |
| 25 | Coco Chanel & Igor Stravinsky | - | - | - | $230,602 | 44 | $230,602 | Aug 6 | Soda Pictures | false |
| 26 | Tooth Fairy | - | - | - | $208,490 | 417 | $6,165,210 | Feb 12 | 20th Century Fox International | false |
| 27 | The Secret in Their Eyes | - | - | - | $133,294 | 16 | $1,166,844 | Aug 13 | Metrodome Distribution | false |
| 28 | Aisha | - | - | - | $84,136 | 25 | $84,136 | Aug 6 | - | false |
