| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Max Th | Opening | % of Total
| Open Th | Open | Close | Distributor
| Estimated
|
|---|
| 1 | Meet the Fockers | - | - | - | $279,261,160 | 3,554 | $46,120,980 | 16.5% | 3,518 | Dec 22 | Jun 16 | Universal Pictures | false |
| 2 | Ocean's Twelve | - | - | - | $125,544,280 | 3,290 | $39,153,380 | 31.2% | 3,290 | Dec 10 | Mar 24 | Warner Bros. | false |
| 3 | A Series of Unfortunate Events | - | - | - | $118,634,549 | 3,623 | $30,061,756 | 25.3% | 3,620 | Dec 17 | Apr 28 | Paramount Pictures | false |
| 4 | The Aviator | - | - | - | $102,610,330 | 2,530 | $858,021 | - | 40 | Dec 17 | Jun 2 | Miramax | true |
| 5 | Million Dollar Baby | - | - | - | $100,492,203 | 2,375 | $179,953 | 0.2% | 8 | Dec 15 | Jun 30 | Warner Bros. | false |
| 6 | Blade: Trinity | - | - | - | $52,411,906 | 2,912 | $16,100,000 | - | 2,912 | Dec 8 | Feb 24 | New Line Cinema | true |
| 7 | The Phantom of the Opera | - | - | - | $51,268,815 | 1,515 | $4,001,890 | 7.8% | 622 | Dec 22 | May 12 | Warner Bros. | false |
| 8 | Fat Albert | - | - | - | $48,116,322 | 2,744 | $10,021,510 | 20.8% | 2,674 | Dec 25 | Apr 7 | Twentieth Century Fox | false |
| 9 | In Good Company | - | - | - | $45,806,659 | 1,963 | $151,750 | 0.3% | 3 | Dec 29 | Mar 31 | Universal Pictures | false |
| 10 | Spanglish | - | - | - | $42,726,869 | 2,587 | $8,817,853 | 20.6% | 2,438 | Dec 17 | Feb 3 | Sony Pictures Releasing | false |
| 11 | Closer | - | - | - | $33,987,757 | 1,098 | $7,707,972 | 22.7% | 476 | Dec 3 | Feb 13 | Sony Pictures Releasing | false |
| 12 | The Life Aquatic with Steve Zissou | - | - | - | $24,020,403 | 1,105 | $113,085 | 0.5% | 2 | Dec 10 | Mar 3 | Walt Disney Studios Motion Pictures | false |
| 13 | Hotel Rwanda | - | - | - | $23,530,892 | 824 | $100,091 | 0.4% | 7 | Dec 22 | Apr 28 | United Artists | false |
| 14 | Darkness | - | - | - | $22,163,442 | 1,718 | $6,400,000 | - | 1,700 | Dec 25 | Mar 10 | Dimension Films | true |
| 15 | Flight of the Phoenix | - | - | - | $21,009,180 | 2,604 | $5,019,430 | 23.9% | 2,604 | Dec 17 | Mar 13 | Twentieth Century Fox | false |
| 16 | House of Flying Daggers | - | - | - | $11,050,094 | 1,189 | $397,472 | - | 15 | Dec 3 | Apr 7 | Sony Pictures Classics | true |
| 17 | Beyond the Sea | - | - | - | $6,318,709 | 383 | $45,264 | 0.7% | 6 | Dec 17 | Mar 31 | Lionsgate | false |
| 18 | The Merchant of Venice | - | - | - | $3,765,585 | 107 | $69,868 | 1.9% | 4 | Dec 29 | May 26 | Sony Pictures Classics | false |
| 19 | Born Into Brothels: Calcutta's Red Light Kids | - | - | - | $3,515,061 | 127 | $14,605 | 0.4% | 1 | Dec 8 | Jul 14 | THINKFilm | false |
| 20 | Ma vie en cinémascope | - | - | - | $2,750,263 | - | - | - | - | Dec 17 | - | Alliance Atlantis Vivafilm | false |
| 21 | The Sea Inside | - | - | - | $2,104,923 | 99 | $55,681 | 2.6% | 23 | Dec 17 | May 19 | Fine Line Features | false |
| 22 | The Woodsman | - | - | - | $1,576,231 | 84 | $53,985 | 3.4% | 6 | Dec 24 | Mar 10 | Newmarket Films | false |
| 23 | Swades | - | - | - | $1,223,240 | 74 | $424,804 | 34.7% | 74 | Dec 17 | Feb 6 | UTV Motion Pictures | false |
| 24 | The Assassination of Richard Nixon | - | - | - | $708,776 | 59 | $37,547 | 5.3% | 5 | Dec 29 | Mar 3 | THINKFilm | false |
| 25 | In the Realms of the Unreal | - | - | - | $417,120 | 13 | $15,477 | 3.7% | 3 | Dec 22 | Jun 16 | Wellspring Media | false |
| 26 | I Am David | - | - | - | $288,552 | 226 | $160,346 | 55.6% | 226 | Dec 3 | Dec 23 | Lionsgate | false |
| 27 | Imaginary Heroes | - | - | - | $228,767 | 24 | $4,696 | 2.1% | 2 | Dec 17 | May 19 | Sony Pictures Classics | false |
| 28 | A Love Song for Bobby Long | - | - | - | $164,308 | 24 | $28,243 | 17.2% | 8 | Dec 29 | Feb 17 | Lionsgate | false |
| 29 | Wonderful Days | - | - | - | $74,663 | 5 | $3,022 | 4% | 1 | Dec 31 | Apr 10 | End Game Productions Inc. | false |
| 30 | A Tale of Two Sisters | - | - | - | $72,541 | 9 | $1,060 | 1.5% | 1 | Dec 3 | May 5 | Tartan | false |
| 31 | After Midnight | - | - | - | $50,469 | 3 | $7,634 | 15.1% | 2 | Dec 3 | Aug 7 | Avatar Films | false |
| 32 | Fabled | - | - | - | $31,425 | 3 | $9,642 | 30.7% | 3 | Dec 10 | May 12 | Indican Pictures | false |
| 33 | WMD: Weapons of Mass Deception | - | - | - | $30,210 | 4 | $4,216 | 14% | 3 | Dec 3 | Feb 17 | Cinema Libre Studio | false |
| 34 | A Talking Picture | - | - | - | $20,237 | 2 | $5,325 | 26.3% | 2 | Dec 10 | Apr 3 | Kino International | false |
| 35 | The Life | - | - | - | $5,130 | 1 | $1,964 | 38.3% | 1 | Dec 17 | - | Screen Media Films | false |
| 36 | Open My Heart | - | - | - | $4,381 | 1 | $2,049 | 46.8% | 1 | Dec 17 | Dec 30 | Strand Releasing | false |
| 37 | Dolls | - | - | - | $4,067 | 1 | $2,067 | 50.8% | 1 | Dec 10 | Dec 19 | Palm Pictures | false |
| 38 | Bandido | - | - | - | $4,064 | 12 | $4,064 | 100% | 12 | Dec 10 | - | Innovation Film Group (IFG) | false |
| 39 | The Green Butchers | - | - | - | $3,783 | 2 | $2,483 | 65.6% | 2 | Dec 10 | Dec 16 | Newmarket Films | false |
| 40 | Conspiracy of Silence | - | - | - | $2,598 | 1 | $2,598 | 100% | 1 | Dec 3 | Dec 5 | Watch Entertainment | false |
| 41 | A Breath | - | - | - | $1,416 | 1 | $1,042 | 73.6% | 1 | Dec 10 | Dec 16 | Kathi Arts | false |
| 42 | Freeze Frame | - | - | - | $1,100 | 1 | $1,100 | 100% | 1 | Dec 10 | Dec 12 | First Look International | false |
| 43 | Producing Adults | - | - | - | $935 | 1 | $459 | 49.1% | 1 | Dec 22 | - | Wolfe Releasing | false |
| 44 | Jesus, You Know | - | - | - | $604 | 1 | $604 | 100% | 1 | Dec 3 | Dec 5 | Leisure Time Features | false |
