Domestic Box Office For January 2010
| Rank | Release | Gross | Max Th | Opening | % of Total | Open Th | Open | Close | Distributor |
|---|---|---|---|---|---|---|---|---|---|
| 1 | The Book of Eli | $94,835,059 | 3,111 | $32,789,494 | 34.6% | 3,111 | Jan 15 | May 13 | Warner Bros. |
| 2 | Tooth Fairy | $60,022,256 | 3,345 | $14,010,409 | 23.3% | 3,344 | Jan 22 | Jun 24 | Twentieth Century Fox |
| 3 | Edge of Darkness | $43,313,890 | 3,066 | $17,214,384 | 39.7% | 3,066 | Jan 29 | Apr 8 | Warner Bros. |
| 4 | Legion | $40,168,080 | 2,476 | $17,501,625 | 43.6% | 2,476 | Jan 22 | Mar 21 | Screen Gems |
| 5 | When in Rome | $32,680,633 | 2,456 | $12,350,041 | 37.8% | 2,456 | Jan 29 | Apr 15 | Walt Disney Studios Motion Pictures |
| 6 | Daybreakers | $30,101,577 | 2,523 | $15,146,692 | 50.3% | 2,523 | Jan 8 | Feb 11 | Lionsgate |
| 7 | Leap Year | $25,918,920 | 2,512 | $9,202,815 | 35.5% | 2,511 | Jan 8 | Mar 4 | Universal Pictures |
| 8 | The Spy Next Door | $24,307,086 | 2,924 | $9,726,056 | 40% | 2,924 | Jan 15 | Mar 4 | Lionsgate |
| 9 | Youth in Revolt | $15,281,286 | 1,873 | $6,888,334 | 45.1% | 1,873 | Jan 8 | Mar 25 | Dimension Films |
| 10 | Extraordinary Measures | $12,068,313 | 2,549 | $6,012,594 | 49.8% | 2,549 | Jan 22 | Feb 11 | CBS Films |
| 11 | The Last Station | $6,617,867 | 354 | $73,723 | 1.1% | 3 | Jan 15 | Jun 24 | Sony Pictures Classics |
| 12 | To Save a Life | $3,777,210 | 441 | $1,581,517 | 41.9% | 441 | Jan 22 | Apr 8 | The Samuel Goldwyn Company |
| 13 | North Face | $711,421 | 36 | $23,050 | 3.2% | 4 | Jan 29 | Jun 17 | Music Box Films |
| 14 | Veer | $527,193 | 92 | $334,562 | 63.5% | 92 | Jan 22 | Feb 11 | Eros Worldwide |
| 15 | Preacher's Kid | $515,065 | 109 | $190,638 | 37% | 109 | Jan 29 | Apr 15 | 8x Entertainment |
| 16 | The Most Dangerous Man in America: Daniel Ellsberg and the Pentagon Papers | $453,993 | 12 | $1,114 | 0.2% | 1 | Jan 29 | Aug 5 | First Run |
| 17 | Fish Tank | $374,675 | 15 | $25,854 | 6.9% | 2 | Jan 15 | May 13 | IFC Films |
| 18 | Creation | $341,323 | 12 | $53,073 | 15.5% | 7 | Jan 22 | May 27 | Newmarket Films |
| 19 | House | $209,765 | 7 | $12,032 | 5.7% | 1 | Jan 15 | Jun 9 | Janus Films |
| 20 | The Girl on the Train | $208,023 | 10 | $19,154 | 9.2% | 2 | Jan 22 | Oct 21 | Strand Releasing |
| 21 | Sweetgrass | $207,473 | 9 | $9,870 | 4.8% | 1 | Jan 6 | Dec 30 | The Cinema Guild |
| 22 | Chance Pe Dance | $168,643 | 68 | $117,917 | 69.9% | 68 | Jan 15 | Jan 28 | UTV Motion Pictures |
| 23 | The Weathered Underground | $140,091 | 22 | $1,010 | 0.7% | 3 | Jan 26 | Apr 8 | Indican Pictures |
| 24 | Saint John of Las Vegas | $102,645 | 14 | $21,666 | 21.1% | 2 | Jan 29 | Mar 4 | IndieVest Pictures |
| 25 | Crazy on the Outside | $88,335 | 75 | $64,438 | 72.9% | 75 | Jan 8 | Jan 14 | Freestyle Releasing |
| 26 | 44 Inch Chest 2010 Re-release | $39,033 | 5 | $4,185 | 10.7% | 1 | Jan 15 | Mar 25 | Image Entertainment |
| 27 | Off and Running | $18,262 | 1 | $7,978 | 43.7% | 1 | Jan 29 | Jul 8 | First Run |
| 28 | Bitch Slap | $17,365 | 3 | $12,254 | 70.6% | 3 | Jan 8 | Jan 21 | Freestyle Releasing |
| 29 | Waiting for Armageddon | $10,501 | 1 | $2,579 | 24.6% | 1 | Jan 8 | Feb 25 | First Run |
| 30 | Brutal Beauty: Tales of the Rose City Rollers | $9,677 | 2 | - | - | - | Jan 8 | - | Cinema Purgatorio |
| 31 | Wonderful World | $9,309 | 4 | $4,582 | 49.2% | 4 | Jan 8 | Jan 21 | Magnolia Pictures |
| 32 | Misconceptions | $6,892 | 2 | $3,796 | 55.1% | 2 | Jan 22 | Apr 15 | Regent Releasing |
| 33 | Watercolors | $6,305 | 2 | $3,207 | 50.9% | 2 | Jan 22 | Apr 15 | Regent Releasing |
| 34 | Fashion Victim | $3,346 | 2 | $1,046 | 31.3% | 2 | Jan 22 | Apr 15 | Regent Releasing |
| 35 | Falling Awake | $1,978 | 2 | $847 | 42.8% | 2 | Jan 29 | Feb 11 | IFC Films |
| 36 | Drool | $1,403 | 1 | $1,199 | 85.5% | 1 | Jan 22 | Jan 28 | Strand Releasing |
