| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Venom: Let There Be Carnage | - | - | - | $192,542,635 | 4,225 | $213,550,366 | Oct 1 | Sony Pictures Releasing | false |
| 2 | No Time to Die | - | - | - | $136,971,408 | 4,407 | $160,891,007 | Oct 8 | Metro-Goldwyn-Mayer (MGM) | false |
| 3 | Shang-Chi and the Legend of the Ten Rings | - | - | - | $128,560,059 | 4,300 | $224,543,292 | Sep 3 | Walt Disney Studios Motion Pictures | false |
| 4 | Halloween Kills | - | - | - | $87,365,075 | 3,727 | $92,002,155 | Oct 15 | Universal Pictures | false |
| 5 | Dune: Part One | - | - | - | $62,554,930 | 4,125 | $108,327,830 | Oct 22 | Warner Bros. | false |
| 6 | The Addams Family 2 | - | - | - | $53,502,233 | 4,207 | $56,489,153 | Oct 1 | United Artists Releasing | false |
| 7 | Free Guy | - | - | - | $27,013,555 | 4,165 | $121,626,598 | Aug 13 | 20th Century Studios | false |
| 8 | Candyman | - | - | - | $20,137,490 | 3,569 | $61,186,570 | Aug 27 | Universal Pictures | false |
| 9 | Dear Evan Hansen | - | - | - | $14,918,020 | 3,364 | $15,002,646 | Sep 24 | Universal Pictures | false |
| 10 | Ron's Gone Wrong | - | - | - | $13,977,325 | 3,560 | $23,009,270 | Oct 22 | 20th Century Studios | false |
| 11 | Malignant | - | - | - | $13,334,116 | 3,501 | $13,391,791 | Sep 10 | Warner Bros. | false |
| 12 | The Last Duel | - | - | - | $10,377,876 | 3,065 | $10,853,945 | Oct 15 | 20th Century Studios | false |
| 13 | Cry Macho | - | - | - | $10,152,908 | 4,022 | $10,310,734 | Sep 17 | Warner Bros. | false |
| 14 | Jungle Cruise | - | - | - | $10,115,971 | 4,310 | $116,987,516 | Jul 30 | Walt Disney Studios Motion Pictures | false |
| 15 | PAW Patrol: The Movie | - | - | - | $8,456,953 | 3,189 | $40,127,371 | Aug 20 | Paramount Pictures | false |
| 16 | My Hero Academia: World Heroes' Mission | - | - | - | $8,213,377 | 1,585 | $12,271,658 | Oct 29 | FUNimation Entertainment | false |
| 17 | The Many Saints of Newark | - | - | - | $7,611,968 | 3,181 | $8,237,403 | Oct 1 | Warner Bros. | false |
| 18 | The French Dispatch | - | - | - | $5,869,072 | 1,225 | $16,124,375 | Oct 22 | Searchlight Pictures | false |
| 19 | Last Night in Soho | - | - | - | $5,838,635 | 3,016 | $10,127,625 | Oct 29 | Focus Features | false |
| 20 | Antlers | - | - | - | $5,605,908 | 2,800 | $10,619,670 | Oct 29 | Searchlight Pictures | false |
| 21 | Copshop | - | - | - | $5,213,243 | 3,005 | $5,213,243 | Sep 17 | Open Road Films (II) | false |
| 22 | Don't Breathe 2 | - | - | - | $4,083,677 | 3,005 | $32,712,950 | Aug 13 | Screen Gems | false |
| 23 | Lamb | - | - | - | $2,676,410 | 865 | $2,676,410 | Oct 8 | A24 | false |
| 24 | The Card Counter | - | - | - | $2,657,850 | 739 | $2,657,850 | Sep 10 | Focus Features | false |
| 25 | The Eyes of Tammy Faye | - | - | - | $2,404,127 | 1,352 | $2,404,127 | Sep 17 | Searchlight Pictures | false |
| 26 | After We Fell | - | - | - | $2,170,750 | 1,294 | $2,170,750 | Sep 10 | Vertical Entertainment | false |
| 27 | Respect | - | - | - | $1,988,824 | 3,207 | $24,278,399 | Aug 13 | Metro-Goldwyn-Mayer (MGM) | false |
| 28 | Show Me the Father | - | - | - | $1,782,909 | 1,073 | $1,803,226 | Sep 10 | Affirm Films | false |
| 29 | The Suicide Squad | - | - | - | $1,505,419 | 4,019 | $55,817,425 | Aug 6 | Warner Bros. | false |
| 30 | Titane | - | - | - | $1,442,988 | 562 | $1,442,988 | Oct 1 | Neon | false |
| 31 | Honsla Rakh | - | - | - | $1,196,000 | 100 | $1,800,000 | Oct 15 | - | false |
| 32 | God's Not Dead: We the People | - | - | - | $1,170,367 | 565 | $1,170,367 | Oct 4 | Fathom Events | false |
| 33 | The Jesus Music | - | - | - | $1,016,725 | 270 | $1,016,725 | Oct 1 | Lionsgate | false |
| 34 | Love Story | - | - | - | $971,000 | 300 | $971,000 | Sep 24 | Sony Pictures Releasing | false |
| 35 | Black Widow | - | - | - | $961,189 | 4,275 | $183,651,655 | Jul 9 | Walt Disney Studios Motion Pictures | false |
| 36 | The Rescue | - | - | - | $946,634 | 561 | $1,060,556 | Oct 8 | Greenwich Entertainment | false |
| 37 | Old | - | - | - | $850,995 | 3,379 | $48,276,510 | Jul 23 | Universal Pictures | false |
| 38 | The Alpinist | - | - | - | $844,743 | 245 | $844,743 | Sep 10 | Roadside Attractions | false |
| 39 | Blue Bayou | - | - | - | $738,175 | 487 | $788,675 | Sep 17 | Focus Features | false |
| 40 | The Night House | - | - | - | $704,876 | 2,240 | $7,100,581 | Aug 20 | Searchlight Pictures | false |
| 41 | Chal Mera Putt 3 | - | - | - | $644,000 | 90 | $644,000 | Oct 1 | Rhythm Boyz Entertainment | false |
| 42 | Courageous 10th Anniversary Re-release | - | - | - | $495,002 | 1,023 | $504,855 | Sep 24 | Affirm Films | false |
| 43 | Space Jam: A New Legacy | - | - | - | $489,803 | 4,002 | $70,592,228 | Jul 16 | Warner Bros. | false |
| 44 | Most Eligible Bachelor | - | - | - | $470,000 | 195 | $470,000 | Oct 15 | - | false |
| 45 | The Protégé | - | - | - | $430,394 | 2,577 | $7,446,823 | Aug 20 | Lionsgate | false |
| 46 | Ghostbusters 2021 Re-release | - | - | - | $391,718 | 774 | $391,718 | Oct 29 | Sony Pictures Classics | false |
| 47 | The Metropolitan Opera HD Live: Mussorgsky: Boris Godunov | - | - | - | $387,000 | 791 | $387,000 | Oct 8 | Fathom Events | false |
| 48 | Ghost in the Shell 2021 4K Remaster | - | - | - | $373,169 | 124 | $373,169 | Sep 17 | Lionsgate | false |
| 49 | The Boss Baby 2: Family Business | - | - | - | $281,785 | 3,688 | $57,300,280 | Jul 2 | Universal Pictures | false |
| 50 | The Lost Leonardo | - | - | - | $271,324 | 217 | $445,740 | Aug 13 | Sony Pictures Classics | false |
| 51 | I'm Your Man | - | - | - | $265,368 | 122 | $275,155 | Sep 24 | Bleecker Street Media | false |
| 52 | Becoming Cousteau | - | - | - | $226,146 | 319 | $231,687 | Oct 22 | Picturehouse | false |
| 53 | Promare | - | - | - | $215,728 | 701 | $2,529,324 | Sep 17 | GKIDS | false |
| 54 | A Mouthful of Air | - | - | - | $212,833 | 816 | $269,435 | Oct 29 | Stage 6 Films | false |
| 55 | Little Eggs: An African Rescue | - | - | - | $183,819 | 320 | $927,154 | Aug 27 | Pantelion Films | false |
| 56 | The Green Knight | - | - | - | $166,244 | 2,798 | $17,173,321 | Jul 30 | A24 | false |
| 57 | My Country, My Parents | - | - | - | $164,811 | 51 | $177,133 | Oct 8 | CMC Pictures | false |
| 58 | Bergman Island | - | - | - | $136,545 | 115 | $145,191 | Oct 15 | IFC Films | false |
| 59 | Stillwater | - | - | - | $136,380 | 2,611 | $14,465,535 | Jul 30 | Focus Features | false |
| 60 | Mass | - | - | - | $131,357 | 59 | $145,174 | Oct 8 | Bleecker Street Media | false |
| 61 | F9: The Fast Saga | - | - | - | $130,290 | 4,203 | $173,005,945 | Jun 25 | Universal Pictures | false |
| 62 | Flag Day | - | - | - | $128,535 | 196 | $424,667 | Aug 20 | United Artists Releasing | false |
| 63 | Small Engine Repair | - | - | - | $110,995 | 205 | $110,995 | Sep 10 | Vertical Entertainment | false |
| 64 | The Forever Purge | - | - | - | $77,275 | 3,058 | $44,539,245 | Jul 2 | Universal Pictures | false |
| 65 | Monster Family 2 | - | - | - | $76,417 | 97 | $76,417 | Oct 15 | Viva Pictures | false |
| 66 | Tango Shalom | - | - | - | $76,099 | 29 | $102,651 | Sep 3 | Vision Films | false |
| 67 | Language Lessons | - | - | - | $73,197 | 44 | $73,257 | Sep 10 | Shout! Factory | false |
| 68 | Hard Luck Love Song | - | - | - | $69,539 | 172 | $69,746 | Oct 15 | Roadside Attractions | false |
| 69 | Reminiscence | - | - | - | $64,424 | 3,265 | $3,900,193 | Aug 20 | Warner Bros. | false |
| 70 | Wife of a Spy | - | - | - | $60,060 | 21 | $69,464 | Sep 17 | Kino Lorber | false |
| 71 | The Nowhere Inn | - | - | - | $54,094 | 48 | $54,094 | Sep 17 | IFC Films | false |
| 72 | Raging Fire | - | - | - | $47,782 | 59 | $385,305 | Aug 13 | Well Go USA Entertainment | false |
| 73 | On Broadway | - | - | - | $47,576 | 63 | $82,733 | Aug 20 | Kino Lorber | false |
| 74 | Azor | - | - | - | $46,678 | 52 | $53,932 | Sep 10 | MUBI | false |
| 75 | Possession 2021 Re-release | - | - | - | $44,935 | 1 | $44,935 | Oct 1 | Metrograph Pictures | false |
| 76 | Old Henry | - | - | - | $42,068 | 30 | $42,068 | Oct 1 | Shout! Factory | false |
| 77 | Nine Days | - | - | - | $40,382 | 443 | $694,849 | Jul 30 | Sony Pictures Classics | false |
| 78 | Breathless 2021 Re-release | - | - | - | $38,001 | 7 | $51,142 | Sep 24 | Rialto Pictures | false |
| 79 | Heart of Champions | - | - | - | $37,000 | 102 | $37,000 | Oct 29 | Vertical Entertainment | false |
| 80 | Falling for Figaro | - | - | - | $34,913 | 44 | $35,910 | Oct 1 | IFC Films | false |
| 81 | 12 Mighty Orphans | - | - | - | $34,741 | 1,047 | $3,689,637 | Jun 11 | Sony Pictures Releasing | false |
| 82 | Mogul Mowgli | - | - | - | $32,767 | 31 | $52,539 | Sep 3 | Strand Releasing | false |
| 83 | The Souvenir: Part II | - | - | - | $32,450 | 42 | $98,929 | Oct 29 | A24 | false |
| 84 | Who You Think I Am | - | - | - | $31,219 | 18 | $45,265 | Sep 3 | Cohen Media Group | false |
| 85 | Golden Voices | - | - | - | $26,585 | 14 | $32,250 | Oct 8 | Music Box Films | false |
| 86 | Yakuza Princess | - | - | - | $24,042 | 63 | $32,124 | Sep 3 | Magnolia Pictures | false |
| 87 | Dating & New York | - | - | - | $21,515 | 38 | $21,515 | Sep 10 | IFC Films | false |
| 88 | Cruella | - | - | - | $20,723 | 3,922 | $86,103,234 | May 28 | Walt Disney Studios Motion Pictures | false |
| 89 | Escape from Mogadishu | - | - | - | $20,383 | 42 | $346,271 | Aug 6 | Well Go USA Entertainment | false |
| 90 | Together | - | - | - | $19,791 | 250 | $214,390 | Aug 27 | Universal Pictures | false |
| 91 | The Swimming Pool 2021 Re-release | - | - | - | $19,173 | 10 | $211,467 | May 14 | Rialto Distribution | false |
| 92 | Learning to Live Together: The Return of Mad Dogs & Englishmen | - | - | - | $18,293 | 4 | $18,293 | Oct 22 | Abramorama | false |
| 93 | In Balanchine's Classroom | - | - | - | $18,211 | 9 | $76,650 | Sep 17 | Zeitgeist Films | false |
| 94 | Ascension | - | - | - | $17,200 | 6 | $17,200 | Oct 8 | MTV Documentary Films | false |
| 95 | Luzzu | - | - | - | $13,756 | 5 | $39,948 | Oct 15 | Kino Lorber | false |
| 96 | The Laws of the Universe: The Age of Elohim | - | - | - | $13,670 | 7 | $15,750 | Oct 22 | Freestyle Releasing | false |
| 97 | Storm Lake | - | - | - | $13,028 | 6 | $13,028 | Sep 17 | Ro*co Films International | false |
| 98 | Swan Song | - | - | - | $12,351 | 48 | $126,110 | Aug 6 | Magnolia Pictures | false |
| 99 | 13 Fanboy | - | - | - | $11,572 | 22 | $11,572 | Oct 22 | Deskpop Entertainment | false |
| 100 | Minyan | - | - | - | $10,639 | 3 | $11,451 | Oct 22 | Strand Releasing | false |
| 101 | Demonic | - | - | - | $10,463 | 85 | $71,334 | Aug 20 | IFC Films | false |
| 102 | Little Girl | - | - | - | $9,394 | 7 | $10,776 | Sep 17 | Music Box Films | false |
| 103 | The Year of the Everlasting Storm | - | - | - | $8,871 | 27 | $12,245 | Sep 3 | Neon | false |
| 104 | Pig | - | - | - | $6,658 | 588 | $3,186,668 | Jul 16 | Neon | false |
| 105 | Ma Belle, My Beauty | - | - | - | $5,894 | 25 | $27,744 | Aug 20 | Good Deed Entertainment | false |
| 106 | We Need to Do Something | - | - | - | $5,863 | 27 | $13,589 | Sep 3 | IFC Films | false |
| 107 | Ailey | - | - | - | $5,782 | 88 | $204,513 | Jul 23 | Neon | false |
| 108 | Only the Animals | - | - | - | $5,704 | 6 | $9,138 | Oct 29 | Cohen Media Group | false |
| 109 | Introducing, Selma Blair | - | - | - | $5,700 | 3 | $5,700 | Oct 15 | Strand Releasing | false |
| 110 | CatVideoFest 2021 | - | - | - | $5,676 | 40 | $93,579 | Jul 23 | Oscilloscope | false |
| 111 | Ema | - | - | - | $5,354 | 27 | $53,437 | Aug 13 | Music Box Films | false |
| 112 | Fire Music | - | - | - | $5,300 | 3 | $11,288 | Sep 10 | Submarine Deluxe | false |
| 113 | Time Is Up | - | - | - | $5,095 | 110 | $5,095 | Sep 9 | Vertical Entertainment | false |
| 114 | Cicada | - | - | - | $4,743 | 4 | $13,370 | Oct 29 | Strand Releasing | false |
| 115 | Without Getting Killed or Caught | - | - | - | $4,705 | 7 | $55,333 | Jul 23 | mTuckman Media | false |
| 116 | Cryptozoo | - | - | - | $4,692 | 45 | $33,765 | Aug 20 | Magnolia Pictures | false |
| 117 | Baking Up Love | - | - | - | $4,457 | - | $8,770 | Aug 28 | - | false |
| 118 | Mayday | - | - | - | $4,382 | 7 | $4,382 | Oct 1 | Magnolia Pictures | false |
| 119 | Confetti | - | - | - | $2,875 | 24 | $33,500 | Aug 20 | Dada Films | false |
| 120 | The Village Detective: A Song Cycle | - | - | - | $2,716 | 1 | $2,839 | Sep 24 | Kino Lorber | false |
| 121 | Shiva Baby | - | - | - | $1,618 | 27 | $159,294 | Apr 2 | Utopia | false |
| 122 | Labyrinth of Cinema | - | - | - | $1,277 | 5 | $4,501 | Oct 20 | MTV Documentary Films | false |
| 123 | Never Gonna Snow Again | - | - | - | $1,192 | 8 | $15,901 | Jul 30 | Kino Lorber | false |
| 124 | The Ladykillers 2021 Re-release | - | - | - | $1,001 | 3 | $23,213 | Jun 4 | Rialto Pictures | false |
| 125 | The Red Circle 2021 Re-release | - | - | - | $937 | 5 | $62,850 | Jun 25 | Rialto Pictures | false |
| 126 | Summer of 85 | - | - | - | $892 | 23 | $71,788 | Jun 18 | Music Box Films | false |
| 127 | The Meaning of Hitler | - | - | - | $790 | 17 | $12,804 | Aug 13 | IFC Films | false |
| 128 | The Incredible 25th Year of Mitzi Bearclaw | - | - | - | $435 | 2 | $12,486 | Feb 12 | Indican Pictures | false |
| 129 | Mama Weed | - | - | - | $414 | 20 | $29,151 | Jul 16 | Music Box Films | false |
| 130 | John and the Hole | - | - | - | $129 | 42 | $25,386 | Aug 6 | IFC Films | false |
| 131 | Lydia Lunch: The War Is Never Over | - | - | - | $63 | 4 | $12,948 | Jun 30 | Kino Lorber | false |
