| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Cars | $3,227,259 | - | 370 | - | $8,722 | $3,227,259 | 1 | Walt Disney Studios Motion Pictures | true | false |
| 2 | - | The Break-Up | $2,276,313 | - | 211 | - | $10,788 | $2,276,313 | 1 | United International Pictures | true | false |
| 3 | 2 | The Da Vinci Code | $1,336,638 | -33.2% | 371 | -122 | $3,602 | $16,889,014 | 4 | United International Pictures | false | false |
| 4 | 1 | X-Men: The Last Stand | $1,188,968 | -47.2% | 290 | -106 | $4,099 | $10,307,071 | 3 | 20th Century Fox International | false | false |
| 5 | - | The Omen | $729,437 | - | 155 | - | $4,706 | $1,102,560 | 1 | 20th Century Fox International | true | false |
| 6 | 3 | Poseidon | $691,703 | -48.8% | 289 | -13 | $2,393 | $2,464,812 | 2 | Warner Bros. | false | false |
| 7 | 4 | Take the Lead | $592,083 | -30% | 129 | +1 | $4,589 | $3,168,469 | 3 | Roadshow Films | false | false |
| 8 | 5 | RV | $563,286 | -23.9% | 181 | - | $3,112 | $1,523,190 | 2 | Sony Pictures Releasing | false | false |
| 9 | 7 | Candy | $136,976 | -24.7% | 44 | +4 | $3,113 | $774,864 | 3 | Dendy Films | false | false |
| 10 | 9 | Separate Lies | $108,048 | -13.3% | 36 | - | $3,001 | $496,520 | 3 | 20th Century Fox International | false | false |
| 11 | 6 | Mission: Impossible III | $92,680 | -62.8% | 61 | -137 | $1,519 | $8,179,198 | 6 | United International Pictures | false | false |
| 12 | - | Caterpillar Wish | $69,151 | - | 24 | - | $2,881 | $94,739 | 1 | Palace Films | true | false |
| 13 | 13 | Caché | $60,923 | -10.8% | 14 | - | $4,351 | $668,422 | 6 | Dendy Films | false | false |
| 14 | 11 | The Three Burials of Melquiades Estrada | $59,354 | -30.3% | 34 | -3 | $1,745 | $314,236 | 3 | Madman Entertainment | false | false |
| 15 | 14 | Ice Age: The Meltdown | $57,957 | -0.2% | 110 | - | $526 | $18,265,807 | 10 | 20th Century Fox International | false | false |
| 16 | 12 | The World's Fastest Indian | $54,647 | -35% | 53 | -31 | $1,031 | $4,713,718 | 10 | Becker Film Group | false | false |
| 17 | 19 | Deep Sea | $49,143 | +43% | 2 | - | $24,571 | $334,977 | 15 | IMAX | false | false |
| 18 | 8 | The Benchwarmers | $36,509 | -75.3% | 56 | -81 | $651 | $1,923,629 | 5 | Sony Pictures Releasing | false | false |
| 19 | 16 | March of the Penguins | $34,829 | -32.5% | 60 | -20 | $580 | $3,091,893 | 11 | Roadshow Films | false | false |
| 20 | 18 | Ballets Russes | $33,857 | -2.6% | 11 | +1 | $3,077 | $189,452 | 4 | Hopscotch Films | false | false |
