| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | What Happens in Vegas | $243,402 | - | 50 | - | $4,868 | $243,402 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Iron Man | $205,313 | -73.5% | 54 | +1 | $3,802 | $1,042,912 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | 21 | $55,292 | -79.3% | 41 | - | $1,348 | $945,406 | 4 | Sony Pictures Releasing | false | false |
| 4 | 4 | Welcome to the Sticks | $49,696 | -78.5% | 53 | -5 | $937 | $9,418,348 | 11 | Alternative Films | false | false |
| 5 | 3 | Fool's Gold | $46,529 | -81% | 25 | - | $1,861 | $341,289 | 2 | Warner Bros. | false | false |
| 6 | 5 | Nim's Island | $30,734 | -86.5% | 60 | -6 | $512 | $269,784 | 2 | Belga Films | false | false |
| 7 | 6 | The Mist | $28,685 | -79.5% | 23 | +2 | $1,247 | $322,380 | 3 | Benelux Film Distributors | false | false |
| 8 | 7 | Taken | $26,720 | -78.8% | 27 | -2 | $989 | $434,654 | 4 | Belga Films | false | false |
| 9 | - | Doomsday | $26,203 | - | 15 | - | $1,746 | $26,203 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 10 | - | Mongol: The Rise of Genghis Khan | $24,392 | - | 12 | - | $2,032 | $24,642 | 1 | Benelux Film Distributors | true | false |
| 11 | 9 | Cash | $23,088 | -79.6% | 20 | - | $1,154 | $270,078 | 3 | Belga Films | false | false |
| 12 | 8 | The Other Boleyn Girl | $22,262 | -81.4% | 38 | - | $585 | $702,747 | 5 | Universal Pictures International (UPI) | false | false |
| 13 | - | Definitely, Maybe | $18,167 | - | 22 | - | $825 | $57,636 | 1 | Universal Pictures International (UPI) | true | false |
| 14 | 14 | REC | $15,010 | -68.4% | 12 | +1 | $1,250 | $74,508 | 2 | Paradiso Entertainment | false | false |
| 15 | - | The Great Alibi | $13,494 | - | 8 | - | $1,686 | $21,316 | 1 | Les Films de l'Elysée | true | false |
| 16 | 13 | U2 3D | $11,374 | -76.6% | 11 | -1 | $1,034 | $340,052 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 17 | 10 | Horton Hears a Who! | $9,894 | -89.8% | 82 | - | $120 | $2,391,907 | 8 | 20th Century Fox International | false | false |
| 18 | - | 120 | $9,542 | - | 3 | - | $3,180 | $9,542 | 1 | N/A | true | false |
| 19 | 16 | The Eye | $9,385 | -79.1% | 16 | -7 | $586 | $419,446 | 5 | Kinepolis Film Distribution (KFD) | false | false |
| 20 | 12 | The Spiderwick Chronicles | $7,146 | -87.2% | 12 | -27 | $595 | $1,506,371 | 8 | Universal Pictures International (UPI) | false | false |
| 21 | 17 | Disco | $6,803 | -83.1% | 19 | -1 | $358 | $793,780 | 6 | Universal Pictures International (UPI) | false | false |
| 22 | 22 | The Ruins | $6,420 | -79.2% | 8 | -4 | $802 | $185,535 | 4 | Universal Pictures International (UPI) | false | false |
| 23 | 20 | Love in the Time of Cholera | $6,292 | -82.8% | 17 | -1 | $370 | $84,831 | 2 | Cinéart | false | false |
| 24 | 18 | Funny Games | $5,978 | -84.2% | 15 | -9 | $398 | $190,485 | 4 | Cinéart | false | false |
| 25 | - | Julia | $5,424 | - | 7 | - | $774 | $8,627 | 1 | Cinéart | true | false |
| 26 | 25 | Untraceable | $5,182 | -79.4% | 8 | -5 | $647 | $1,021,774 | 10 | Kinepolis Film Distribution (KFD) | false | false |
| 27 | 27 | I've Loved You So Long | $5,017 | -77.2% | 23 | +6 | $218 | $461,737 | 8 | Benelux Film Distributors | false | false |
| 28 | 11 | Meet the Spartans | $4,885 | -92.3% | 16 | - | $305 | $775,091 | 6 | 20th Century Fox International | false | false |
| 29 | - | Bhoothnath | $4,822 | - | 1 | - | $4,822 | $4,822 | 1 | N/A | true | false |
| 30 | 26 | The Band's Visit | $4,601 | -80.3% | 8 | -1 | $575 | $76,422 | 3 | Paradiso Entertainment | false | false |
| 31 | 24 | Moscow, Belgium | $3,968 | -84.4% | 6 | -2 | $661 | $1,629,630 | 15 | Kinepolis Film Distribution (KFD) | false | false |
| 32 | 29 | 10,000 BC | $3,257 | -84.7% | 11 | - | $296 | $2,433,421 | 9 | Warner Bros. | false | false |
| 33 | 21 | Winx Club: The Secret of the Lost Kingdom | $3,073 | -91.5% | 23 | +11 | $133 | $552,169 | 7 | Independent Films | false | false |
| 34 | 15 | Hotel op stelten | $2,510 | -94.5% | 28 | -6 | $89 | $1,189,393 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 35 | 34 | Linkeroever | $2,467 | -82.4% | 5 | - | $493 | $349,020 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 36 | 23 | Never Back Down | $2,199 | -91.4% | 6 | -9 | $366 | $80,768 | 3 | Paradiso Entertainment | false | false |
| 37 | 19 | Step Up 2: The Streets | $2,077 | -94.4% | 20 | -5 | $103 | $3,392,928 | 11 | Benelux Film Distributors | false | false |
| 38 | 43 | The Darjeeling Limited | $2,036 | -51.2% | 5 | - | $407 | $222,652 | 8 | 20th Century Fox International | false | false |
| 39 | 32 | Vantage Point | $2,019 | -88.2% | 6 | -9 | $336 | $914,670 | 7 | Sony Pictures Releasing | false | false |
| 40 | 30 | Les randonneurs à Saint-Tropez | $1,987 | -89.9% | 14 | -6 | $141 | $304,716 | 5 | Belga Films | false | false |
| 41 | 35 | Dragon Hunters | $1,764 | -87.3% | 20 | +1 | $88 | $361,933 | 7 | Belga Films | false | false |
| 42 | 36 | No Country for Old Men | $1,684 | -86.1% | 7 | -2 | $240 | $1,831,633 | 16 | Universal Pictures International (UPI) | false | false |
| 43 | 28 | Fly Me to the Moon 3D | $1,431 | -93.3% | 9 | -2 | $159 | $1,058,818 | 15 | Kinepolis Film Distribution (KFD) | false | false |
| 44 | 42 | The Kite Runner | $1,028 | -78.6% | 14 | -4 | $73 | $805,106 | 13 | Universal Pictures International (UPI) | false | false |
| 45 | 40 | Formidable | $860 | -88.1% | 2 | -3 | $430 | $9,921 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 46 | 38 | 27 Dresses | $644 | -93.9% | 4 | - | $161 | $1,167,226 | 10 | 20th Century Fox International | false | false |
| 47 | 46 | Once | $173 | -88% | 3 | - | $57 | $39,398 | 10 | Paradiso Entertainment | false | false |
| 48 | 50 | Redacted | $93 | -61.4% | 2 | - | $46 | $15,864 | 11 | Paradiso Entertainment | false | false |
