| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Hancock | $19,003,359 | - | 450 | - | $42,229 | $19,003,359 | 1 | Sony Pictures Releasing | true | false |
| 2 | - | Kung Fu Panda | $12,028,694 | - | 446 | - | $26,970 | $12,028,694 | 1 | Paramount Pictures International | true | false |
| 3 | 1 | The Chronicles of Narnia: Prince Caspian | $4,052,525 | -50% | 541 | -5 | $7,490 | $15,275,161 | 2 | Walt Disney Pictures | false | false |
| 4 | 2 | Wanted | $2,458,979 | -67.7% | 402 | -10 | $6,116 | $13,084,885 | 2 | Universal Pictures International (UPI) | false | false |
| 5 | 6 | Sex and the City | $559,970 | -52.5% | 209 | -173 | $2,679 | $50,514,758 | 6 | Entertainment Film Distributors | false | false |
| 6 | 5 | Indiana Jones and the Kingdom of the Crystal Skull | $541,700 | -56.6% | 327 | -95 | $1,656 | $78,331,177 | 7 | Paramount Pictures International | false | false |
| 7 | 4 | Adulthood | $535,279 | -58.7% | 179 | +3 | $2,990 | $5,940,093 | 3 | Pathé | false | false |
| 8 | - | The Mist | $311,918 | - | 188 | - | $1,659 | $311,918 | 1 | Momentum Pictures | true | false |
| 9 | 3 | The Incredible Hulk | $232,447 | -82.2% | 309 | -125 | $752 | $15,976,655 | 4 | Universal Pictures International (UPI) | false | false |
| 10 | 7 | The Edge of Love | $217,483 | -58.5% | 104 | -73 | $2,091 | $1,738,498 | 3 | Lionsgate | false | false |
| 11 | 11 | Gone Baby Gone | $100,535 | -42% | 53 | -29 | $1,896 | $3,215,511 | 5 | Walt Disney Pictures | false | false |
| 12 | - | Love Story 2050 | $97,354 | - | 38 | - | $2,561 | $97,354 | 1 | - | true | false |
| 13 | - | The Visitor | $96,651 | - | 19 | - | $5,086 | $96,651 | 1 | Halcyon Pictures | true | false |
| 14 | 10 | Thoda Pyaar Thoda Magic | $82,451 | -68.3% | 35 | -14 | $2,355 | $473,706 | 2 | Yash Raj Films | false | false |
| 15 | 12 | Female Agents | $71,944 | -47.3% | 34 | -15 | $2,116 | $311,290 | 2 | Revolver Entertainment | false | false |
| 16 | - | Jaane Tu... Ya Jaane Na | $59,843 | - | 13 | - | $4,603 | $59,843 | 1 | UTV Motion Pictures | true | false |
| 17 | 14 | The Secret of the Grain | $49,826 | -1.6% | 11 | +3 | $4,529 | $246,585 | 3 | Artificial Eye | false | false |
| 18 | 8 | The Happening | $41,044 | -91.7% | 86 | -204 | $477 | $8,002,392 | 4 | 20th Century Fox International | false | false |
| 19 | 18 | Priceless | $25,920 | -29.7% | 13 | -17 | $1,993 | $743,908 | 4 | Icon Film Distribution | false | false |
| 20 | 17 | Mongol: The Rise of Genghis Khan | $21,934 | -43.7% | 12 | -18 | $1,827 | $1,383,670 | 5 | The Works UK Distribution | false | false |
| 21 | 9 | Superhero Movie | $21,100 | -92.4% | 87 | -172 | $242 | $5,366,040 | 5 | Momentum Pictures | false | false |
| 22 | 21 | In Search of a Midnight Kiss | $20,680 | -29.5% | 6 | -6 | $3,446 | $367,854 | 4 | Vertigo Films | false | false |
| 23 | - | My Winnipeg | $19,148 | - | 4 | - | $4,787 | $19,148 | 1 | Soda Pictures | true | false |
| 24 | 27 | Underdog | $17,761 | +54.8% | 56 | +27 | $317 | $3,022,519 | 23 | Walt Disney Pictures | false | false |
| 25 | 20 | A Complete History of My Sexual Failures | $14,055 | -54.6% | 8 | -4 | $1,756 | $67,017 | 2 | Optimum Releasing | false | false |
| 26 | 15 | What Happens in Vegas | $11,778 | -75.4% | 11 | -23 | $1,070 | $15,698,125 | 9 | 20th Century Fox International | false | false |
| 27 | 16 | Iron Man | $11,250 | -72.2% | 23 | -55 | $489 | $34,093,930 | 10 | Paramount Pictures International | false | false |
| 28 | 19 | Nim's Island | $10,927 | -65.5% | 40 | -57 | $273 | $7,605,842 | 10 | Universal Pictures International (UPI) | false | false |
| 29 | - | Muniyandi Vilangiyal Moonramandu | $9,730 | - | 3 | - | $3,243 | $9,730 | 1 | Ayngaran International | true | false |
| 30 | 23 | Mere Baap Pehle Aap | $7,796 | -63.6% | 12 | -3 | $649 | $500,757 | 4 | - | false | false |
| 31 | 28 | Caramel | $6,562 | +0.2% | 7 | +2 | $937 | $906,138 | 8 | Momentum Pictures | false | false |
| 32 | 31 | Let's Get Lost | $6,145 | +10.2% | 5 | - | $1,229 | $91,472 | 5 | - | false | false |
| 33 | 32 | Welcome to the Sticks | $5,741 | +38.5% | 3 | +1 | $1,913 | $231,167 | 14 | Pathé | false | false |
| 34 | 13 | Teeth | $4,687 | -95.5% | 15 | -107 | $312 | $938,462 | 3 | Momentum Pictures | false | false |
| 35 | - | My Friends, My Love | $4,479 | - | 1 | - | $4,479 | $4,479 | 1 | Pathé | true | false |
| 36 | 33 | Persepolis | $3,767 | -6.1% | 2 | - | $1,883 | $1,722,410 | 11 | Optimum Releasing | false | false |
| 37 | 29 | Killer of Sheep 2008 Re-release | $3,728 | -41.3% | 1 | -1 | $3,728 | $37,105 | 3 | British Film Institute (BFI) | false | false |
| 38 | 51 | Cassandra's Dream | $3,375 | +690.4% | 4 | +2 | $843 | $227,295 | 7 | Optimum Releasing | false | false |
| 39 | 39 | The Diving Bell and the Butterfly | $2,802 | +43.3% | 2 | +1 | $1,401 | $1,795,783 | 22 | Pathé | false | false |
| 40 | - | Death Note: The Last Name 2008 Re-release | $2,120 | - | 2 | - | $1,060 | $2,120 | 1 | - | true | false |
| 41 | 38 | Speed Racer | $2,067 | -9.8% | 8 | -4 | $258 | $3,211,062 | 9 | Warner Bros. | false | false |
| 42 | - | Chop Suey 2008 Re-release | $1,516 | - | 1 | - | $1,516 | $1,516 | 1 | - | true | false |
| 43 | 50 | The Orphanage | $1,358 | +139.1% | 1 | - | $1,358 | $3,489,104 | 16 | Optimum Releasing | false | false |
| 44 | 43 | Taxi to the Dark Side | $1,326 | -2.5% | 1 | - | $1,326 | $15,781 | 4 | Revolver Entertainment | false | false |
| 45 | 49 | XXY | $1,088 | +49.5% | 3 | +1 | $362 | $120,981 | 9 | Peccadillo Pictures | false | false |
| 46 | 45 | Heartbeat Detector | $818 | -28.3% | 1 | -2 | $818 | $153,268 | 8 | Trinity Filmed Entertainment | false | false |
| 47 | 37 | Jules and Jim 2008 Re-release | $731 | -74.1% | 2 | -1 | $365 | $158,920 | 6 | British Film Institute (BFI) | false | false |
| 48 | - | Her Name Is Sabine | $711 | - | 1 | - | $711 | $5,985 | 3 | ICA Films | false | false |
| 49 | 30 | Happy-Go-Lucky | $606 | -89.5% | 1 | -7 | $606 | $3,142,124 | 12 | Momentum Pictures | false | false |
| 50 | 54 | Son of Rambow | $458 | +38.4% | 2 | +1 | $229 | $8,281,562 | 14 | Optimum Releasing | false | false |
| 51 | 52 | Irina Palm | $216 | -49.2% | 1 | - | $216 | $3,551 | 4 | Soda Pictures | false | false |
| 52 | 53 | Private Property | $184 | -46.4% | 1 | -1 | $184 | $61,946 | 12 | Soda Pictures | false | false |
| 53 | - | Some Came Running | $109 | - | 1 | - | $109 | $26,215 | 8 | British Film Institute (BFI) | false | false |
| 54 | 56 | California Dreamin' | $63 | -23.2% | 2 | +1 | $31 | $58,096 | 6 | Artificial Eye | false | false |
| 55 | - | The Aerial | $63 | - | 1 | - | $63 | $11,922 | - | Periscoop Film | - | false |
| 56 | 58 | You, the Living | $40 | - | 1 | - | $40 | $199,358 | 15 | Artificial Eye | false | false |
| 57 | 47 | Manufactured Landscapes | $40 | -95.9% | 1 | -1 | $40 | $42,753 | 9 | British Film Institute (BFI) | false | false |
| 58 | 42 | The Last Mistress | $40 | -97.3% | 1 | -1 | $40 | $85,660 | 13 | Artificial Eye | false | false |
| 59 | 59 | Lars and the Real Girl | $40 | - | 1 | - | $40 | $885,232 | 16 | Verve Pictures | false | false |
