| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Revolutionary Road | $330,473 | - | 43 | - | $7,685 | $351,744 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Yes Man | $258,388 | -15.7% | 60 | - | $4,306 | $1,727,564 | 4 | Warner Bros. | false | false |
| 3 | 2 | Seven Pounds | $227,015 | -21.6% | 30 | - | $7,567 | $559,543 | 2 | Sony Pictures Releasing | false | false |
| 4 | 3 | De l'autre côté du lit | $192,936 | -26% | 28 | +2 | $6,890 | $806,256 | 3 | Belga Films | false | false |
| 5 | 5 | Twilight | $186,715 | -13.6% | 54 | - | $3,457 | $2,861,977 | 9 | Belga Films | false | false |
| 6 | 6 | Slumdog Millionaire | $183,668 | +6.8% | 18 | +2 | $10,203 | $391,708 | 2 | Cinéart | false | false |
| 7 | 4 | Madagascar: Escape 2 Africa | $161,505 | -30.9% | 100 | -4 | $1,615 | $6,538,065 | 8 | Universal Pictures International (UPI) | false | false |
| 8 | 7 | Australia | $82,436 | -37.6% | 70 | -10 | $1,177 | $1,749,240 | 6 | 20th Century Fox International | false | false |
| 9 | 12 | Loft | $75,550 | +2.8% | 30 | - | $2,518 | $9,234,501 | 14 | Independent Films | false | false |
| 10 | 8 | The Duchess | $70,462 | -40.5% | 29 | - | $2,429 | $379,142 | 3 | Cinéart | false | false |
| 11 | 9 | Beauties at War | $65,171 | -44.8% | 18 | - | $3,620 | $203,197 | 2 | Belga Films | false | false |
| 12 | 10 | Burn After Reading | $62,107 | -23.1% | 32 | +1 | $1,940 | $1,527,545 | 7 | Universal Pictures International (UPI) | false | false |
| 13 | 11 | Bedtime Stories | $53,203 | -29.1% | 45 | -2 | $1,182 | $979,408 | 5 | Walt Disney Pictures | false | false |
| 14 | - | Special Correspondents | $46,269 | - | 16 | - | $2,891 | $46,756 | 1 | Victory Productions | true | false |
| 15 | 13 | Transporter 3 | $42,984 | -32.2% | 25 | -3 | $1,719 | $1,358,922 | 7 | Belga Films | false | false |
| 16 | 16 | The Flight Before Christmas | $41,426 | -18.6% | 31 | +1 | $1,336 | $628,431 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 17 | - | Eden Lake | $40,692 | - | 7 | - | $5,813 | $40,953 | 1 | Benelux Film Distributors | true | false |
| 18 | 14 | Frost/Nixon | $30,164 | -50.2% | 19 | -1 | $1,587 | $102,078 | 2 | Universal Pictures International (UPI) | false | false |
| 19 | 18 | Piet Piraat en het zwaard van Zilvertand | $29,780 | -24.9% | 29 | -3 | $1,026 | $595,695 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 20 | 21 | Trouble at Timpetill | $29,664 | -8.5% | 14 | - | $2,118 | $512,561 | 6 | Alternative Films | false | false |
| 21 | 15 | The Day the Earth Stood Still | $27,629 | -54.4% | 20 | -20 | $1,381 | $2,102,505 | 7 | 20th Century Fox International | false | false |
| 22 | 17 | Two Lovers | $25,294 | -40.5% | 13 | -1 | $1,945 | $445,043 | 5 | Cinéart | false | false |
| 23 | 19 | Afterwards | $24,087 | -32.7% | 11 | - | $2,189 | $67,107 | 2 | Victory Productions | false | false |
| 24 | - | Private Lessons | $22,745 | - | 9 | - | $2,527 | $31,842 | 1 | Cinéart | true | false |
| 25 | - | Elite Squad | $20,026 | - | 9 | - | $2,225 | $38,117 | 1 | Benelux Film Distributors | true | false |
| 26 | 20 | The Heir Apparent: Largo Winch | $17,540 | -49.9% | 16 | -1 | $1,096 | $589,134 | 6 | Cinéart | false | false |
| 27 | 23 | Il Divo | $15,583 | -34.3% | 9 | - | $1,731 | $56,981 | 2 | ABC Distribution | false | false |
| 28 | 22 | Winter in Wartime | $15,275 | -43.6% | 14 | +1 | $1,091 | $341,918 | 8 | Benelux Film Distributors | false | false |
| 29 | 37 | Welcome to the Sticks | $13,847 | +127.5% | 5 | +1 | $2,769 | $10,689,903 | 48 | Alternative Films | false | false |
| 30 | 24 | The Broken | $13,432 | -42.9% | 5 | - | $2,686 | $102,151 | 2 | Paradiso Entertainment | false | false |
| 31 | - | A Man and His Dog | $12,114 | - | 9 | - | $1,346 | $16,545 | 1 | Les Films de l'Elysée | true | false |
| 32 | 47 | Pride and Glory | $11,622 | +552.2% | 3 | +1 | $3,874 | $219,151 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 33 | 29 | Changeling | $10,292 | -29.9% | 10 | -5 | $1,029 | $1,039,829 | 11 | Universal Pictures International (UPI) | false | false |
| 34 | 25 | Blinker en de blixvaten | $9,979 | -42.1% | 19 | -5 | $525 | $281,026 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 35 | 26 | Quantum of Solace | $8,619 | -45.8% | 3 | -1 | $2,873 | $4,733,245 | 12 | Sony Pictures Releasing | false | false |
| 36 | 27 | Appaloosa | $7,204 | -54.3% | 4 | -3 | $1,801 | $84,108 | 3 | Paradiso Entertainment | false | false |
| 37 | 30 | High School Musical 3: Senior Year | $7,060 | -48.4% | 6 | -2 | $1,176 | $2,827,517 | 13 | Walt Disney Pictures | false | false |
| 38 | - | Les grandes personnes | $6,263 | - | 7 | - | $894 | $6,428 | 1 | N/A | true | false |
| 39 | 36 | Stella | $5,763 | -19.2% | 6 | - | $960 | $14,233 | 2 | Benelux Film Distributors | false | false |
| 40 | 31 | Wild Child | $5,418 | -50.4% | 7 | -2 | $774 | $208,514 | 5 | Universal Pictures International (UPI) | false | false |
| 41 | 39 | Anubis en het Pad der 7 Zonden | $3,840 | -7.6% | 2 | -1 | $1,920 | $1,506,707 | 15 | Kinepolis Film Distribution (KFD) | false | false |
| 42 | 35 | Christmas in Paris | $3,823 | -47.8% | 9 | -1 | $424 | $225,792 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 43 | 41 | Modern Life | $3,817 | - | 2 | -1 | $1,908 | $54,061 | 12 | Benelux Film Distributors | false | false |
| 44 | 28 | Saw V | $2,930 | -80.2% | 6 | -4 | $488 | $665,938 | 6 | Les Films de l'Elysée | false | false |
| 45 | - | Religulous | $2,456 | - | 4 | - | $614 | $2,456 | 1 | A-Film Distribution | true | false |
| 46 | 50 | Hunger | $771 | +29.1% | 4 | +1 | $192 | $39,890 | 11 | Paradiso Entertainment | false | false |
| 47 | 53 | Moscow, Belgium | $767 | +123.6% | 2 | +1 | $383 | $1,883,987 | 52 | Kinepolis Film Distribution (KFD) | false | false |
| 48 | 40 | Anything for Her | $622 | -84.5% | 4 | -9 | $155 | $76,712 | 4 | Benelux Film Distributors | false | false |
| 49 | 51 | Home | $465 | +25% | 2 | -2 | $232 | $55,898 | 11 | Benelux Film Distributors | false | false |
| 50 | - | A Wonderful Night in Split | $427 | - | 1 | - | $427 | $427 | 1 | N/A | true | false |
| 51 | 46 | Elegy | $326 | -81.8% | 8 | +2 | $40 | $191,011 | 14 | Kinepolis Film Distribution (KFD) | false | false |
| 52 | 54 | A Pain in the Ass | $261 | -1.5% | 1 | -1 | $261 | $78,045 | 7 | Benelux Film Distributors | false | false |
| 53 | 56 | The Wave | $87 | +107.1% | 1 | - | $87 | $55,308 | 14 | Paradiso Entertainment | false | false |
