| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Terminator Salvation | $2,046,199 | - | 516 | - | $3,965 | $2,046,199 | 1 | Sony Pictures Releasing | true | false |
| 2 | 2 | Night at the Museum: Battle of the Smithsonian | $1,179,757 | -43.8% | 398 | -94 | $2,964 | $7,475,101 | 3 | 20th Century Fox International | false | false |
| 3 | 1 | Angels & Demons | $1,176,650 | -53.5% | 647 | -164 | $1,818 | $23,692,309 | 4 | Sony Pictures Releasing | false | false |
| 4 | 3 | The Girl with the Dragon Tattoo | $794,309 | -39.1% | 414 | -23 | $1,918 | $3,213,223 | 2 | BIM Distribuzione | false | false |
| 5 | 4 | Vincere | $309,272 | -43.5% | 227 | -64 | $1,362 | $2,322,096 | 3 | 01 Distribution | false | false |
| 6 | 5 | Coco Before Chanel | $306,061 | -29.6% | 164 | +1 | $1,866 | $1,123,386 | 2 | Warner Bros. | false | false |
| 7 | - | Cash | $262,919 | - | 136 | - | $1,933 | $262,919 | 1 | N/A | true | false |
| 8 | 6 | My Bloody Valentine | $182,042 | -54.1% | 78 | -17 | $2,333 | $8,157,374 | 5 | Medusa Distribuzione | false | false |
| 9 | 7 | 17 Again | $101,187 | -61.5% | 82 | -84 | $1,233 | $2,119,820 | 4 | Warner Bros. | false | false |
| 10 | - | Visions | $63,937 | - | - | - | - | $63,937 | 1 | N/A | true | false |
| 11 | 9 | Battle for Terra | $50,926 | -57.1% | 125 | -5 | $407 | $282,660 | 2 | Sony Pictures Releasing | false | false |
| 12 | 8 | Antichrist | $46,332 | -68.9% | 51 | -64 | $908 | $635,338 | 3 | Lucky Red | false | false |
| 13 | - | L'amour | $36,038 | - | - | - | - | $36,038 | 1 | N/A | true | false |
| 14 | 10 | Star Trek | $35,975 | -66.6% | 28 | -41 | $1,284 | $3,127,646 | 5 | United International Pictures | false | false |
| 15 | 12 | State of Play | $33,957 | -38.6% | 18 | -15 | $1,886 | $3,295,951 | 6 | United International Pictures | false | false |
| 16 | 14 | Questione di cuore | $28,925 | -10.6% | 14 | -4 | $2,066 | $3,665,801 | 8 | 01 Distribution | false | false |
| 17 | 15 | Gran Torino | $28,637 | -4.2% | 14 | -4 | $2,045 | $12,407,903 | 13 | Warner Bros. | false | false |
| 18 | 16 | Cloud 9 | $25,820 | -7.5% | 17 | - | $1,518 | $84,906 | 2 | Warner Bros. | false | false |
| 19 | 20 | The Milk of Sorrow | $13,618 | -1.4% | 10 | -2 | $1,361 | $236,458 | 5 | N/A | false | false |
| 20 | - | The Tale of Despereaux | $12,779 | - | 14 | - | $912 | $652,375 | 7 | United International Pictures | false | false |
