| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Harry Potter and the Half-Blood Prince | $1,090,687 | - | 97 | - | $11,244 | $1,090,687 | 1 | Warner Bros. | true | false |
| 2 | 1 | Ice Age: Dawn of the Dinosaurs | $506,440 | -30.8% | 89 | - | $5,690 | $3,317,276 | 3 | 20th Century Fox International | false | false |
| 3 | 2 | The Proposal | $187,975 | -27.2% | 58 | -1 | $3,240 | $575,639 | 2 | Zon Lusomundo Audiovisuais | false | false |
| 4 | 3 | Brüno | $97,314 | -29.1% | 38 | - | $2,560 | $306,826 | 2 | Sony Pictures Releasing | false | false |
| 5 | 5 | The Hangover | $77,580 | -25.3% | 52 | - | $1,491 | $1,148,997 | 5 | Warner Bros. | false | false |
| 6 | 4 | Transformers: Revenge of the Fallen | $51,492 | -52.7% | 54 | -17 | $953 | $1,341,948 | 4 | Zon Lusomundo Audiovisuais | false | false |
| 7 | - | Fighting | $30,892 | - | 20 | - | $1,544 | $30,892 | 1 | United International Pictures | true | false |
| 8 | - | The Young Victoria | $18,486 | - | 8 | - | $2,310 | $18,486 | 1 | Prisvídeo | true | false |
| 9 | 6 | State of Play | $16,151 | -58.2% | 12 | -29 | $1,345 | $529,563 | 5 | Zon Lusomundo Audiovisuais | false | false |
| 10 | 7 | The Last House on the Left | $13,304 | -55.1% | 25 | -4 | $532 | $123,458 | 3 | United International Pictures | false | false |
| 11 | 8 | Angels & Demons | $4,569 | -73.1% | 4 | -16 | $1,142 | $3,226,555 | 10 | Sony Pictures Releasing | false | false |
| 12 | 11 | Terminator Salvation | $717 | -85.8% | 4 | -10 | $179 | $1,000,365 | 7 | Sony Pictures Releasing | false | false |
