| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Phobia 2 | $230,023 | - | 23 | - | $10,001 | $230,023 | 1 | Panasia Films | true | false |
| 2 | 2 | District 9 | $211,792 | -57.4% | 33 | - | $6,417 | $848,470 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | 500 Days of Summer | $211,193 | - | 21 | - | $10,056 | $211,193 | 1 | 20th Century Fox International | true | false |
| 4 | - | Whiteout | $174,558 | - | 30 | - | $5,818 | $174,558 | 1 | Warner Bros. | true | false |
| 5 | - | April Bride | $134,652 | - | 18 | - | $7,480 | $134,652 | 1 | N/A | true | false |
| 6 | 1 | The Founding of a Republic | $120,071 | -76% | 38 | +2 | $3,159 | $751,042 | 2 | Newport Entertainment | false | false |
| 7 | 3 | Garfield's Pet Force | $58,378 | -83.1% | 26 | -8 | $2,245 | $449,019 | 2 | Panasia Films | false | false |
| 8 | 5 | The Time Traveler's Wife | $48,414 | -72.3% | 17 | -6 | $2,847 | $581,629 | 3 | Lark Films Distribution | false | false |
| 9 | - | Split Second Murders | $43,102 | - | 28 | - | $1,539 | $43,102 | 1 | Newport Entertainment | true | false |
| 10 | 4 | Surrogates | $42,308 | -87% | 21 | -16 | $2,014 | $1,136,356 | 3 | Walt Disney Pictures | false | false |
| 11 | 6 | Fame | $39,077 | -75% | 17 | -8 | $2,298 | $235,865 | 2 | Golden Scene | false | false |
| 12 | 10 | Taking Woodstock | $12,167 | -56.6% | 5 | -1 | $2,433 | $49,148 | 2 | Edko Films | false | false |
| 13 | 7 | The Proposal | $10,550 | -86.5% | 7 | -15 | $1,507 | $1,608,028 | 5 | Walt Disney Pictures | false | false |
| 14 | 9 | The Final Destination | $6,784 | -79.9% | 4 | -12 | $1,696 | $1,441,016 | 4 | Warner Bros. | false | false |
| 15 | 8 | Accident | $4,765 | -87.2% | 3 | -11 | $1,588 | $691,396 | 4 | Newport Entertainment | false | false |
| 16 | - | Shrink | $3,669 | - | 1 | - | $3,669 | $3,669 | 1 | Deltamac Co. | true | false |
| 17 | 15 | My Sister's Keeper | $2,461 | -4.4% | 1 | -1 | $2,461 | $175,096 | 6 | Warner Bros. | false | false |
| 18 | 11 | Tidal Wave | $1,202 | -94.6% | 2 | -11 | $601 | $490,898 | 4 | Edko Films | false | false |
| 19 | 16 | Lorna's Silence | $137 | -92% | 1 | -1 | $137 | $7,861 | 3 | N/A | false | false |
| 20 | 14 | Up | $32 | -98.8% | 1 | -1 | $32 | $4,325,709 | 11 | Walt Disney Pictures | false | false |
