| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Avatar | $104,874 | -18.5% | 8 | - | $13,109 | $1,246,962 | 7 | 20th Century Fox International | false | false |
| 2 | - | The Book of Eli | $40,581 | - | 8 | - | $5,072 | $40,581 | 1 | - | true | false |
| 3 | 2 | Sherlock Holmes | $27,268 | -19.2% | 8 | - | $3,408 | $260,647 | 5 | Warner Bros. | false | false |
| 4 | - | Did You Hear About the Morgans? | $16,534 | - | 5 | - | $3,306 | $16,534 | 1 | Sony Pictures Releasing | true | false |
| 5 | 3 | Nine | $12,002 | -49.8% | 4 | - | $3,000 | $41,351 | 2 | N/A | false | false |
| 6 | 6 | Alvin and the Chipmunks: The Squeakquel | $8,198 | -6.6% | 3 | - | $2,732 | $85,163 | 6 | 20th Century Fox International | false | false |
| 7 | 5 | 2012 | $7,240 | -25.9% | 6 | -2 | $1,206 | $1,083,728 | 12 | Sony Pictures Releasing | false | false |
| 8 | 7 | The Princess and the Frog | $7,177 | +2.6% | 2 | - | $3,588 | $44,553 | 5 | Walt Disney Pictures | false | false |
| 9 | - | Franklyn | $6,868 | - | 3 | - | $2,289 | $6,868 | 1 | N/A | true | false |
| 10 | 4 | Old Dogs | $5,480 | -53.8% | 2 | -1 | $2,740 | $65,655 | 4 | Walt Disney Pictures | false | false |
| 11 | - | High Lane | $4,633 | - | 5 | - | $926 | $4,633 | 1 | N/A | true | false |
| 12 | 8 | Ninja Assassin | $1,468 | -78% | 3 | -2 | $489 | $35,607 | 4 | Warner Bros. | false | false |
| 13 | 13 | Love Happens | $1,103 | +3.9% | 1 | - | $1,103 | $49,301 | 6 | N/A | false | false |
| 14 | 9 | Armored | $1,059 | -83.2% | 3 | - | $353 | $8,115 | 2 | Sony Pictures Releasing | false | false |
| 15 | - | Arthur and the Revenge of Maltazard | $847 | - | 2 | - | $423 | $847 | 1 | N/A | true | false |
| 16 | 14 | Cirque du Freak: The Vampire's Assistant | $787 | -16.5% | 2 | -1 | $393 | $33,947 | 8 | United International Pictures | false | false |
| 17 | 17 | Case 39 | $334 | -25.1% | 2 | -1 | $167 | $94,084 | 10 | United International Pictures | false | false |
| 18 | 12 | The Twilight Saga: New Moon | $150 | -91.2% | 2 | -1 | $75 | $536,061 | 10 | - | false | false |
| 19 | 10 | The Box | $137 | -97.7% | 1 | -2 | $137 | $22,983 | 3 | N/A | false | false |
| 20 | 21 | Surrogates | $120 | +93.5% | 1 | - | $120 | $130,897 | 17 | Walt Disney Pictures | false | false |
| 21 | 15 | Couples Retreat | $91 | -87% | 1 | -1 | $91 | $97,334 | 10 | United International Pictures | false | false |
| 22 | 16 | How to Lose Friends & Alienate People | $6 | -98.8% | 1 | -1 | $6 | $10,515 | 3 | N/A | false | false |
