| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 3 | The Princess and the Frog | $1,027,649 | +131.9% | 63 | -12 | $16,311 | $2,669,954 | 3 | Walt Disney Pictures | false | false |
| 2 | 1 | Avatar | $790,938 | +39.3% | 133 | -15 | $5,946 | $13,730,249 | 10 | 20th Century Fox International | false | false |
| 3 | 2 | Percy Jackson & the Olympians: The Lightning Thief | $705,416 | +36.2% | 80 | - | $8,817 | $1,475,782 | 2 | 20th Century Fox International | false | false |
| 4 | 4 | Valentine's Day | $463,654 | +7.6% | 48 | - | $9,659 | $1,062,956 | 2 | 20th Century Fox International | false | false |
| 5 | 6 | Bo | $396,802 | +51.2% | 21 | +1 | $18,895 | $793,578 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 6 | 5 | The Wolfman | $314,882 | -20.2% | 36 | - | $8,746 | $834,350 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | 8 | Planet 51 | $296,140 | +114.2% | 60 | -1 | $4,935 | $606,536 | 2 | Belga Films | false | false |
| 8 | - | Edge of Darkness | $290,674 | - | 44 | - | $6,606 | $305,744 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 9 | - | The Pimp | $253,383 | - | 18 | - | $14,076 | $253,383 | 1 | Belga Films | true | false |
| 10 | 12 | Alvin and the Chipmunks: The Squeakquel | $252,651 | +164.8% | 48 | -17 | $5,263 | $4,337,590 | 9 | 20th Century Fox International | false | false |
| 11 | 19 | Cloudy with a Chance of Meatballs | $177,968 | +315.8% | 33 | +4 | $5,392 | $978,433 | 6 | Sony Pictures Releasing | false | false |
| 12 | - | I Love You Phillip Morris | $170,259 | - | 27 | - | $6,305 | $191,613 | 1 | Belga Films | true | false |
| 13 | 7 | The Lovely Bones | $130,535 | -15.1% | 33 | - | $3,955 | $402,481 | 2 | Universal Pictures International (UPI) | false | false |
| 14 | 9 | Sherlock Holmes | $100,764 | -25.2% | 38 | -24 | $2,651 | $2,733,170 | 7 | Warner Bros. | false | false |
| 15 | 13 | Oceans | $97,374 | +9.7% | 26 | - | $3,745 | $596,843 | 4 | Alternative Films | false | false |
| 16 | 14 | The Imaginarium of Doctor Parnassus | $78,533 | -7% | 16 | - | $4,908 | $272,187 | 2 | Kinepolis Film Distribution (KFD) | false | false |
| 17 | 11 | Up in the Air | $75,057 | -24.5% | 18 | -7 | $4,169 | $1,050,134 | 5 | Universal Pictures International (UPI) | false | false |
| 18 | 10 | The Book of Eli | $71,155 | -40.4% | 26 | -6 | $2,736 | $526,086 | 3 | Paradiso Entertainment | false | false |
| 19 | 16 | Dossier K. | $66,401 | -7.4% | 17 | -9 | $3,905 | $3,671,101 | 11 | Kinepolis Film Distribution (KFD) | false | false |
| 20 | 15 | Gainsbourg: A Heroic Life | $63,063 | -21.2% | 21 | +1 | $3,003 | $381,733 | 3 | Cinéart | false | false |
| 21 | 18 | A Serious Man | $44,519 | +4% | 11 | - | $4,047 | $406,933 | 5 | Universal Pictures International (UPI) | false | false |
| 22 | - | Fantastic Mr. Fox | $40,825 | - | 17 | - | $2,401 | $40,825 | 1 | 20th Century Fox International | true | false |
| 23 | 17 | Did You Hear About the Morgans? | $37,890 | -43.1% | 18 | -9 | $2,105 | $737,899 | 4 | Sony Pictures Releasing | false | false |
| 24 | 20 | Invictus | $32,144 | -16.9% | 8 | -10 | $4,018 | $699,430 | 6 | Warner Bros. | false | false |
| 25 | 26 | Plop en de kabouterbaby | $32,047 | +132.1% | 14 | -5 | $2,289 | $1,530,426 | 11 | Kinepolis Film Distribution (KFD) | false | false |
| 26 | 25 | Vincere | $24,005 | +28.2% | 8 | - | $3,000 | $53,406 | 2 | ABC Distribution | false | false |
| 27 | 22 | Mr. Nobody | $23,327 | -8.6% | 15 | -4 | $1,555 | $790,763 | 6 | Belga Films | false | false |
| 28 | 30 | Anubis en de wraak van Arghus | $22,258 | +188.5% | 6 | -4 | $3,709 | $1,045,845 | 10 | Kinepolis Film Distribution (KFD) | false | false |
| 29 | 23 | The Road | $19,118 | -19.7% | 13 | -11 | $1,470 | $357,194 | 4 | Benelux Film Distributors | false | false |
| 30 | 21 | OceanWorld | $18,629 | -33% | 7 | -8 | $2,661 | $65,116 | 2 | N/A | false | false |
| 31 | 28 | The Barons | $10,760 | +25.9% | 11 | - | $978 | $1,285,858 | 16 | Cinéart | false | false |
| 32 | 35 | The Girl Who Played with Fire | $10,536 | +76.9% | 7 | -3 | $1,505 | $186,189 | 6 | Benelux Film Distributors | false | false |
| 33 | - | Silent Voice | $9,215 | - | 4 | - | $2,303 | $9,215 | 1 | Cinéart | true | false |
| 34 | 27 | It's Complicated | $8,653 | -13.2% | 3 | -11 | $2,884 | $1,455,263 | 9 | Universal Pictures International (UPI) | false | false |
| 35 | 24 | Protéger & servir | $7,037 | -66.8% | 6 | -3 | $1,172 | $101,915 | 3 | Alternative Films | false | false |
| 36 | 29 | Angel at Sea | $6,779 | -17% | 3 | - | $2,259 | $18,556 | 2 | N/A | false | false |
| 37 | 38 | Paranormal Activity | $6,621 | +23.2% | 7 | +3 | $945 | $1,150,266 | 13 | Kinepolis Film Distribution (KFD) | false | false |
| 38 | 39 | The Men Who Stare at Goats | $5,308 | +72.6% | 1 | -2 | $5,308 | $290,768 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 39 | 32 | No One Knows About Persian Cats | $5,015 | -29.2% | 3 | -1 | $1,671 | $47,918 | 4 | Cinéart | false | false |
| 40 | - | 4, 5, 6... Mélie pain d'épice | $4,521 | - | 2 | - | $2,260 | $5,545 | 1 | N/A | true | false |
| 41 | 34 | The Concert | $4,313 | -27.6% | 10 | -1 | $431 | $821,511 | 15 | Cinéart | false | false |
| 42 | 41 | Das Lied der Dinge | $3,076 | +29.3% | 3 | -3 | $1,025 | $3,584,466 | 20 | Kinepolis Film Distribution (KFD) | false | false |
| 43 | 31 | Brothers | $3,044 | -57.1% | 8 | -3 | $380 | $313,467 | 9 | A-Film Distribution | false | false |
| 44 | 40 | Altiplano | $3,031 | +10.2% | 3 | - | $1,010 | $148,862 | 13 | N/A | false | false |
| 45 | 44 | Arthur and the Revenge of Maltazard | $2,201 | +60.9% | 6 | -2 | $366 | $2,097,280 | 12 | Belga Films | false | false |
| 46 | 33 | Bright Star | $2,067 | -70.1% | 3 | -2 | $689 | $133,313 | 11 | Paradiso Entertainment | false | false |
| 47 | 36 | Capitalism: A Love Story | $1,584 | -70.6% | 3 | -3 | $528 | $162,408 | 7 | Paradiso Entertainment | false | false |
| 48 | 43 | The Ordinary People | $1,489 | +0.3% | 4 | -1 | $372 | $27,561 | 5 | Cinéart | false | false |
| 49 | 37 | Horse | $1,293 | -75.9% | 3 | -2 | $431 | $26,676 | 2 | Cinéart | false | false |
| 50 | 42 | Coco Chanel & Igor Stravinsky | $1,121 | -31.4% | 4 | -2 | $280 | $77,413 | 7 | Cinéart | false | false |
| 51 | 45 | The Twilight Saga: New Moon | $704 | -43.4% | 3 | -4 | $234 | $6,760,388 | 14 | Belga Films | false | false |
