| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Alice in Wonderland | $1,025,794 | - | 80 | - | $12,822 | $1,025,794 | 1 | Walt Disney Pictures | true | false |
| 2 | 1 | Shutter Island | $214,109 | -38.7% | 54 | -3 | $3,964 | $1,585,684 | 3 | United International Pictures | false | false |
| 3 | 2 | The Princess and the Frog | $141,164 | -46.9% | 74 | -23 | $1,907 | $1,234,787 | 3 | Walt Disney Pictures | false | false |
| 4 | 4 | East End Angels | $90,442 | -30% | 48 | -4 | $1,884 | $265,501 | 2 | Nordisk Film | false | false |
| 5 | 3 | Avatar | $88,579 | -65.3% | 24 | -15 | $3,690 | $13,563,659 | 12 | 20th Century Fox International | false | false |
| 6 | 5 | The Junior Olsen Gang and the Master Thief | $72,462 | -35% | 55 | -8 | $1,317 | $1,924,153 | 6 | Nordisk Film | false | false |
| 7 | - | The Lovely Bones | $70,895 | - | 45 | - | $1,575 | $79,094 | 1 | United International Pictures | true | false |
| 8 | - | Edge of Darkness | $66,826 | - | 26 | - | $2,570 | $67,469 | 1 | Nordisk Film | true | false |
| 9 | 6 | Valentine's Day | $41,989 | -51.4% | 21 | -4 | $1,999 | $835,639 | 4 | Sandrew Metronome Distribution Sverige AB | false | false |
| 10 | 11 | Crazy Heart | $34,983 | -32.6% | 26 | -7 | $1,345 | $144,138 | 2 | 20th Century Fox International | false | false |
| 11 | 7 | Percy Jackson & the Olympians: The Lightning Thief | $34,505 | -59.1% | 36 | -17 | $958 | $654,674 | 4 | 20th Century Fox International | false | false |
| 12 | 10 | The Road | $32,136 | -47.8% | 10 | -11 | $3,213 | $278,886 | 3 | Scanbox Entertainment | false | false |
| 13 | 9 | The Wolfman | $28,246 | -57.2% | 27 | -25 | $1,046 | $716,818 | 4 | United International Pictures | false | false |
| 14 | 12 | Alvin and the Chipmunks: The Squeakquel | $27,811 | -44% | 14 | -14 | $1,986 | $3,277,483 | 11 | 20th Century Fox International | false | false |
| 15 | 13 | Ploddy the Police Car Makes a Splash | $22,319 | -40.1% | 27 | -18 | $826 | $1,386,225 | 9 | Nordisk Film | false | false |
| 16 | 8 | Cloudy with a Chance of Meatballs | $19,952 | -72.7% | 33 | +8 | $604 | $1,267,238 | 8 | Sony Pictures Releasing | false | false |
| 17 | 14 | Fantastic Mr. Fox | $18,300 | -50.7% | 29 | -11 | $631 | $416,612 | 5 | 20th Century Fox International | false | false |
| 18 | 15 | A Single Man | $16,400 | -31.6% | 5 | - | $3,280 | $182,908 | 4 | Svensk Filmindustri (SF) | false | false |
| 19 | 16 | Precious | $16,302 | -30.5% | 8 | -3 | $2,037 | $367,479 | 6 | N/A | false | false |
| 20 | 20 | Sherlock Holmes | $13,466 | -6.1% | 8 | -6 | $1,683 | $3,196,245 | 11 | Warner Bros. | false | false |
| 21 | 17 | Fish Tank | $12,466 | -31% | 6 | -2 | $2,077 | $104,203 | 3 | Arthouse | false | false |
| 22 | 19 | Empty Barrels | $6,339 | -59.7% | 9 | -14 | $704 | $1,672,496 | 9 | N/A | false | false |
| 23 | 23 | Did You Hear About the Morgans? | $5,998 | +1.2% | 25 | +12 | $239 | $434,202 | 6 | Sony Pictures Releasing | false | false |
| 24 | 18 | It's Complicated | $5,141 | -70% | 5 | -11 | $1,028 | $1,833,896 | 11 | United International Pictures | false | false |
| 25 | 24 | The Imaginarium of Doctor Parnassus | $675 | -51.3% | 6 | -2 | $112 | $371,065 | 11 | Sony Pictures Releasing | false | false |
