| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Despicable Me | $500,304 | -5.8% | 79 | +1 | $6,332 | $1,124,816 | 2 | United International Pictures | false | false |
| 2 | - | Life as We Know It | $212,435 | - | 49 | - | $4,335 | $212,435 | 1 | Warner Bros. | true | false |
| 3 | 2 | The Town | $159,516 | -8.3% | 52 | -4 | $3,067 | $724,244 | 3 | Warner Bros. | false | false |
| 4 | 3 | Eat Pray Love | $129,755 | -17.3% | 57 | -4 | $2,276 | $1,724,672 | 5 | Sony Pictures Releasing | false | false |
| 5 | - | Paranormal Activity 2 | $120,897 | - | 27 | - | $4,477 | $120,897 | 1 | Zon Lusomundo Audiovisuais | true | false |
| 6 | 4 | The Other Guys | $83,095 | -14.1% | 29 | -1 | $2,865 | $212,548 | 2 | Sony Pictures Releasing | false | false |
| 7 | 5 | The Last Exorcism | $39,118 | -35.7% | 27 | -6 | $1,448 | $257,326 | 3 | Zon Lusomundo Audiovisuais | false | false |
| 8 | 6 | Wall Street: Money Never Sleeps | $27,110 | -29.6% | 19 | -13 | $1,426 | $859,594 | 6 | Castello Lopes Multimédia | false | false |
| 9 | - | Ondine | $22,765 | - | 4 | - | $5,691 | $22,765 | 1 | N/A | true | false |
| 10 | 10 | The Switch | $20,316 | -3% | 19 | +1 | $1,069 | $558,163 | 7 | Prisvídeo | false | false |
| 11 | 11 | Let Me In | $14,919 | -26.9% | 15 | - | $994 | $46,928 | 2 | Castello Lopes Multimédia | false | false |
| 12 | 12 | Loose Cannons | $14,405 | -5.3% | 4 | - | $3,601 | $74,051 | 4 | Prisvídeo | false | false |
| 13 | 8 | Legend of the Guardians: The Owls of Ga'Hoole | $14,246 | -50.3% | 13 | -19 | $1,095 | $422,371 | 4 | Warner Bros. | false | false |
| 14 | 9 | The New Daughter | $12,453 | -41.3% | 10 | - | $1,245 | $42,355 | 2 | Prisvídeo | false | false |
| 15 | 7 | Vampires Suck | $11,902 | -59.7% | 15 | -10 | $793 | $385,584 | 5 | Zon Lusomundo Audiovisuais | false | false |
| 16 | 16 | Inception | $8,790 | +16.5% | 7 | -2 | $1,255 | $2,590,508 | 15 | Warner Bros. | false | false |
| 17 | 13 | Dinner for Schmucks | $8,232 | -29.7% | 6 | -7 | $1,372 | $765,675 | 8 | Zon Lusomundo Audiovisuais | false | false |
| 18 | 14 | Hachi: A Dog's Tale | $7,673 | -18.8% | 7 | -3 | $1,096 | $149,497 | 5 | Zon Lusomundo Audiovisuais | false | false |
| 19 | 26 | The Secret in Their Eyes | $6,649 | +110.1% | 3 | - | $2,216 | $215,497 | 24 | N/A | false | false |
| 20 | 17 | Gainsbourg: A Heroic Life | $6,347 | -15.1% | 5 | +1 | $1,269 | $18,840 | 2 | Zon Lusomundo Audiovisuais | false | false |
| 21 | - | Charlie St. Cloud | $6,180 | - | 15 | - | $412 | $211,348 | 4 | Zon Lusomundo Audiovisuais | false | false |
| 22 | 18 | Tinker Bell and the Great Fairy Rescue | $5,413 | -21.9% | 6 | -2 | $902 | $98,550 | 5 | Zon Lusomundo Audiovisuais | false | false |
| 23 | - | Predators | $4,624 | - | 12 | - | $385 | $409,666 | 9 | Castello Lopes Multimédia | false | false |
| 24 | 23 | The Karate Kid | $3,548 | +1.9% | 5 | -4 | $709 | $985,562 | 9 | Sony Pictures Releasing | false | false |
| 25 | 27 | Hideaway | $3,518 | +15.3% | 2 | - | $1,759 | $7,835 | 2 | N/A | false | false |
| 26 | 20 | The Sorcerer's Apprentice | $3,475 | -40.2% | 7 | -6 | $496 | $1,407,159 | 10 | Walt Disney Pictures | false | false |
| 27 | 15 | Pandorum | $3,151 | -64.9% | 6 | -11 | $525 | $40,543 | 3 | Zon Lusomundo Audiovisuais | false | false |
| 28 | 21 | Regrets | $3,093 | -20.3% | 2 | - | $1,546 | $14,598 | 3 | N/A | false | false |
| 29 | 29 | Toy Story 3 | $2,936 | +25.3% | 5 | - | $587 | $3,561,450 | 14 | Zon Lusomundo Audiovisuais | false | false |
| 30 | 25 | Salt | $2,520 | -23.2% | 3 | -2 | $840 | $1,503,545 | 11 | Sony Pictures Releasing | false | false |
| 31 | 19 | The Boys Are Back | $2,515 | -62.7% | 3 | -1 | $838 | $50,092 | 4 | Zon Lusomundo Audiovisuais | false | false |
| 32 | 30 | Resident Evil: Afterlife | $2,327 | +11% | 6 | -1 | $387 | $1,186,780 | 7 | Sony Pictures Releasing | false | false |
| 33 | 31 | Step Up 3D | $2,139 | +13.4% | 1 | - | $2,139 | $638,864 | 8 | Zon Lusomundo Audiovisuais | false | false |
| 34 | 28 | Brothers | $1,900 | -23.3% | 5 | - | $380 | $151,946 | 9 | Prisvídeo | false | false |
| 35 | 33 | Cats & Dogs: The Revenge of Kitty Galore | $1,048 | -7.9% | 5 | +2 | $209 | $398,968 | 9 | Warner Bros. | false | false |
| 36 | 32 | The Ghost Writer | $975 | -25.9% | 2 | +1 | $487 | $535,491 | 16 | Zon Lusomundo Audiovisuais | false | false |
| 37 | 22 | Going the Distance | $901 | -74.2% | 3 | -3 | $300 | $229,273 | 6 | Warner Bros. | false | false |
| 38 | 35 | MacGruber | $643 | -9.9% | 2 | -1 | $321 | $33,271 | 4 | Castello Lopes Multimédia | false | false |
| 39 | 36 | Daybreakers | $210 | -67.9% | 7 | +5 | $30 | $59,366 | 5 | LNK Filmes | false | false |
| 40 | 24 | [Rec]² | $168 | -95% | 3 | -4 | $56 | $58,184 | 4 | Zon Lusomundo Audiovisuais | false | false |
