| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Harry Potter and the Deathly Hallows: Part 2 | $430,564 | -64.9% | 103 | +7 | $4,180 | $1,919,924 | 2 | NuMetro Distribution | false | false |
| 2 | 2 | Cars 2 | $220,738 | -46.5% | 86 | -2 | $2,566 | $2,153,956 | 3 | Ster-Kinekor Pictures | false | false |
| 3 | - | Horrible Bosses | $193,632 | - | 51 | - | $3,796 | $193,632 | 1 | NuMetro Distribution | true | false |
| 4 | 3 | Transformers: Dark of the Moon | $189,967 | -32.3% | 64 | -4 | $2,968 | $3,223,839 | 4 | United International Pictures | false | false |
| 5 | - | Honey 2 | $98,948 | - | 35 | - | $2,827 | $98,948 | 1 | United International Pictures | true | false |
| 6 | 4 | Something Borrowed | $68,632 | -42.1% | 48 | -3 | $1,429 | $542,851 | 3 | NuMetro Distribution | false | false |
| 7 | 5 | Madea's Big Happy Family | $58,513 | -32.1% | 35 | - | $1,671 | $667,501 | 4 | Ster-Kinekor Pictures | false | false |
| 8 | 6 | Bridesmaids | $49,138 | -37.2% | 35 | -16 | $1,403 | $925,093 | 5 | United International Pictures | false | false |
| 9 | - | The Bang Bang Club | $48,896 | - | 53 | - | $922 | $48,896 | 1 | Indigenous Film Distribution | true | false |
| 10 | 7 | Kung Fu Panda 2 | $33,378 | -56.4% | 34 | -16 | $981 | $3,069,209 | 7 | United International Pictures | false | false |
| 11 | 8 | The Hangover Part II | $33,122 | -52% | 39 | -16 | $849 | $2,668,096 | 9 | NuMetro Distribution | false | false |
| 12 | - | Insidious | $25,551 | - | 15 | - | $1,703 | $25,551 | 1 | NuMetro Distribution | true | false |
| 13 | 10 | Mr. Popper's Penguins | $20,332 | -56% | 31 | -14 | $655 | $850,958 | 6 | NuMetro Distribution | false | false |
| 14 | 9 | Scream 4 | $14,175 | -77.3% | 23 | -32 | $616 | $333,438 | 3 | Ster-Kinekor Pictures | false | false |
| 15 | 11 | Pirates of the Caribbean: On Stranger Tides | $12,485 | -58.9% | 12 | -10 | $1,040 | $3,596,579 | 10 | Ster-Kinekor Pictures | false | false |
| 16 | 14 | Jumping the Broom | $10,300 | -24.4% | 12 | -3 | $858 | $351,944 | 6 | Ster-Kinekor Pictures | false | false |
| 17 | - | Biutiful | $9,931 | - | 3 | - | $3,310 | $9,931 | 1 | Ster-Kinekor Pictures | true | false |
| 18 | 16 | The Lincoln Lawyer | $8,556 | -22.7% | 9 | +1 | $950 | $452,742 | 8 | NuMetro Distribution | false | false |
| 19 | - | Chalet Girl | $7,966 | - | 10 | - | $796 | $7,966 | 1 | United International Pictures | true | false |
| 20 | 15 | All Good Things 2010 Re-release | $7,182 | -35.9% | 6 | -3 | $1,197 | $156,191 | 5 | Ster-Kinekor Pictures | false | false |
| 21 | 12 | Green Lantern | $6,955 | -64.7% | 11 | -18 | $632 | $947,398 | 5 | NuMetro Distribution | false | false |
| 22 | 19 | Roepman | $3,579 | -37.2% | 9 | - | $397 | $341,660 | 10 | Ster-Kinekor Pictures | false | false |
| 23 | 20 | The Adjustment Bureau | $3,141 | -11.5% | 8 | +2 | $392 | $359,034 | 7 | United International Pictures | false | false |
| 24 | 18 | Fast Five | $1,303 | -78.5% | 3 | -6 | $434 | $2,686,639 | 12 | United International Pictures | false | false |
| 25 | 22 | My Hunter's Heart | $373 | -70.5% | 1 | -1 | $373 | $4,261 | 3 | United International Pictures | false | false |
